| SP | Greinke, Z.Greinke, Zack † | Fisher Cats | R | 77.0 | 18 | 18 | 9 | 4 | 3.01 | .256 | 1.02 | 7.4 | 1.8 | 6.7 | 131.2 | 108 | 44 | 44 | 11 | 26 | 98 | 4 | 0 | 0 | 0 | 13 | 2 | 3 | 3.24 |
| SP | Harvey, M.Harvey, Matt † $$ | Fisher Cats | R | 75.0 | 17 | 17 | 10 | 4 | 3.19 | .257 | 1.00 | 6.7 | 2.3 | 7.9 | 118.1 | 88 | 42 | 42 | 5 | 30 | 103 | 1 | 0 | 0 | 1 | 11 | 5 | 3 | 2.69 |
| SP | Fernandez, J.Fernandez, Jose † $ | Fisher Cats | R | 72.0 | 19 | 19 | 9 | 5 | 2.93 | .279 | 1.12 | 6.8 | 3.2 | 9.0 | 120.0 | 91 | 41 | 39 | 6 | 43 | 120 | 0 | 0 | 0 | 0 | 15 | 5 | 3 | 2.85 |
| CL | Kimbrel, C.Kimbrel, Craig † $$ | Corporation | R | 67.5 | 32 | 0 | 4 | 5 | 3.93 | .270 | 1.11 | 6.6 | 3.4 | 11.1 | 34.1 | 25 | 15 | 15 | 6 | 13 | 42 | 0 | 21 | 1 | 0 | 0 | 0 | 1 | 3.97 |
| SP | Buchholz, C.Buchholz, Clay | Fisher Cats | R | 66.0 | 18 | 18 | 9 | 5 | 3.19 | .297 | 1.24 | 7.8 | 3.4 | 8.0 | 118.1 | 102 | 45 | 42 | 11 | 45 | 105 | 0 | 0 | 0 | 0 | 13 | 3 | 1 | 3.65 |
| SP | deGrom, J.deGrom, Jacob # | Spiders | R | 60.0 | 19 | 19 | 9 | 6 | 4.02 | .269 | 1.10 | 8.3 | 1.7 | 9.8 | 134.1 | 123 | 60 | 60 | 20 | 25 | 146 | 1 | 0 | 0 | 0 | 11 | 0 | 3 | 3.32 |