| SP | Kluber, C.Kluber, Corey † | Indians | R | 178.0 | 33 | 33 | 19 | 5 | 2.84 | .251 | 0.99 | 6.5 | 2.5 | 8.3 | 256.2 | 185 | 82 | 81 | 28 | 70 | 237 | 10 | 0 | 0 | 3 | 26 | 3 | 5 | 3.43 |
| SP | Hunter, C.Hunter, Catfish † | Athletics Tres | R | 131.0 | 38 | 38 | 18 | 13 | 3.78 | .288 | 1.20 | 8.2 | 2.7 | 5.3 | 266.2 | 241 | 126 | 112 | 29 | 80 | 156 | 17 | 0 | 0 | 2 | 21 | 3 | 6 | 4.18 |
| SP | Martinez, P.Martinez, Pedro † | M9ts | R | 130.0 | 36 | 1 | 18 | 9 | 3.02 | .285 | 1.19 | 7.9 | 2.8 | 6.4 | 205.1 | 181 | 72 | 69 | 17 | 64 | 145 | 1 | 0 | 0 | 1 | 1 | 1 | 5 | 3.61 |
| SP | Darvish, Y.Darvish, Yu † # | Padres | R | 130.0 | 37 | 37 | 16 | 13 | 3.03 | .285 | 1.18 | 8.1 | 2.5 | 7.8 | 258.1 | 233 | 92 | 87 | 21 | 71 | 224 | 1 | 0 | 0 | 1 | 22 | 5 | 7 | 3.21 |
| CL | Hendriks, L.Hendriks, Liam † | Beige Underwear | R | 125.0 | 68 | 0 | 5 | 5 | 4.16 | .269 | 1.09 | 7.7 | 2.1 | 9.3 | 67.0 | 57 | 31 | 31 | 14 | 16 | 69 | 0 | 42 | 6 | 0 | 0 | 1 | 4 | 4.42 |
| SP | De La Rosa, J.De La Rosa, Jorge | Rockies | L | 118.5 | 68 | 0 | 22 | 3 | 4.73 | .332 | 1.47 | 8.3 | 5.0 | 5.5 | 161.2 | 149 | 92 | 85 | 19 | 89 | 98 | 0 | 1 | 0 | 0 | 0 | 3 | 12 | 5.03 |