| SP | Kluber, C.Kluber, Corey † | Indians | R | 181.0 | 32 | 32 | 19 | 5 | 2.71 | .249 | 0.98 | 6.4 | 2.4 | 8.3 | 252.0 | 180 | 77 | 76 | 26 | 68 | 231 | 10 | 0 | 0 | 3 | 26 | 3 | 4 | 3.35 |
| SP | Hunter, C.Hunter, Catfish † | Athletics Tres | R | 130.0 | 33 | 33 | 17 | 9 | 3.61 | .280 | 1.16 | 7.7 | 2.7 | 5.5 | 232.0 | 199 | 107 | 93 | 23 | 69 | 141 | 15 | 0 | 0 | 2 | 19 | 3 | 6 | 4.00 |
| SP | Martinez, P.Martinez, Pedro † | M9ts | R | 121.0 | 34 | 0 | 17 | 8 | 3.07 | .290 | 1.22 | 8.2 | 2.8 | 6.2 | 193.1 | 176 | 69 | 66 | 17 | 60 | 134 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 3.70 |
| SP | Fernandez, S.Fernandez, Sid | M9ts | L | 119.0 | 33 | 33 | 15 | 8 | 3.30 | .295 | 1.23 | 6.7 | 4.4 | 8.1 | 218.1 | 162 | 82 | 80 | 22 | 107 | 197 | 2 | 0 | 0 | 1 | 23 | 5 | 1 | 4.05 |
| SP | Darvish, Y.Darvish, Yu † # | Padres | R | 116.0 | 33 | 33 | 14 | 11 | 3.06 | .280 | 1.14 | 8.1 | 2.2 | 8.1 | 232.0 | 209 | 84 | 79 | 20 | 56 | 210 | 1 | 0 | 0 | 1 | 20 | 5 | 7 | 3.10 |
| CL | Hendriks, L.Hendriks, Liam † | Beige Underwear | R | 115.5 | 65 | 0 | 5 | 5 | 4.36 | .273 | 1.11 | 7.9 | 2.1 | 9.3 | 64.0 | 56 | 31 | 31 | 14 | 15 | 66 | 0 | 39 | 6 | 0 | 0 | 1 | 4 | 4.53 |