| SP | deGrom, J.deGrom, Jacob † | Yeti | R | 179.0 | 34 | 34 | 22 | 8 | 2.31 | .239 | 0.92 | 6.3 | 2.0 | 9.4 | 221.2 | 155 | 59 | 57 | 17 | 50 | 231 | 1 | 0 | 0 | 0 | 29 | 4 | 0 | 2.64 |
| SP | Buehler, W.Buehler, Walker † # | Yeti | R | 149.0 | 33 | 33 | 19 | 7 | 2.69 | .266 | 1.07 | 6.4 | 3.3 | 8.1 | 201.0 | 143 | 61 | 60 | 16 | 73 | 182 | 1 | 0 | 0 | 1 | 22 | 3 | 7 | 3.36 |
| SP | Arrieta, J.Arrieta, Jake † | Athletics | R | 145.0 | 34 | 34 | 18 | 8 | 3.06 | .262 | 1.04 | 6.6 | 2.8 | 8.9 | 232.2 | 169 | 83 | 79 | 25 | 73 | 230 | 3 | 0 | 0 | 0 | 24 | 6 | 5 | 3.44 |
| CL | Feliz, N.Feliz, Neftali † | Fiction | R | 139.5 | 65 | 0 | 4 | 7 | 2.82 | .292 | 1.22 | 6.3 | 4.7 | 8.7 | 67.0 | 47 | 25 | 21 | 4 | 35 | 65 | 0 | 47 | 5 | 0 | 0 | 1 | 0 | 3.45 |
| CL | Street, H.Street, Huston † | Ninjas | R | 125.5 | 71 | 0 | 5 | 8 | 2.76 | .275 | 1.12 | 6.2 | 3.9 | 10.6 | 78.1 | 54 | 24 | 24 | 5 | 34 | 92 | 0 | 37 | 2 | 0 | 0 | 1 | 4 | 2.82 |
| SP | Verlander, J.Verlander, Justin † | Ninjas | R | 119.0 | 34 | 34 | 16 | 12 | 3.41 | .282 | 1.13 | 6.9 | 3.3 | 9.4 | 232.0 | 179 | 94 | 88 | 33 | 84 | 243 | 2 | 0 | 0 | 1 | 24 | 10 | 2 | 3.97 |