| SP | Koufax, S.Koufax, Sandy † | Mets | L | 112.0 | 18 | 18 | 11 | 4 | 2.27 | .245 | 0.94 | 6.3 | 2.2 | 7.9 | 146.2 | 102 | 38 | 37 | 11 | 36 | 128 | 9 | 0 | 0 | 2 | 13 | 5 | 3 | 3.07 |
| SP | Alexander, P.Alexander, Pete † | Mets | R | 101.0 | 17 | 17 | 14 | 2 | 3.21 | .287 | 1.20 | 7.4 | 3.4 | 5.7 | 126.0 | 104 | 47 | 45 | 10 | 47 | 80 | 4 | 0 | 0 | 0 | 13 | 1 | 3 | 3.90 |
| SP | deGrom, J.deGrom, Jacob † $$ | Warriors | R | 83.0 | 18 | 18 | 10 | 7 | 2.63 | .251 | 1.01 | 7.2 | 1.9 | 9.2 | 130.0 | 104 | 43 | 38 | 13 | 27 | 133 | 1 | 0 | 0 | 1 | 14 | 0 | 0 | 2.88 |
| SP | Leonard, D.Leonard, Dutch | Mets | L | 73.0 | 17 | 17 | 10 | 2 | 3.03 | .268 | 1.09 | 6.8 | 2.9 | 5.6 | 104.0 | 79 | 35 | 35 | 7 | 34 | 65 | 0 | 0 | 0 | 0 | 12 | 1 | 2 | 3.63 |
| SP | Verlander, J.Verlander, Justin † # | SPARTICISTS | R | 69.0 | 18 | 18 | 10 | 4 | 3.87 | .273 | 1.11 | 7.9 | 2.1 | 8.3 | 109.1 | 96 | 48 | 47 | 11 | 25 | 100 | 3 | 0 | 0 | 3 | 9 | 2 | 0 | 3.22 |
| SP | Johnson, W.Johnson, Walter | Astros | R | 67.0 | 18 | 18 | 10 | 5 | 4.05 | .284 | 1.17 | 8.4 | 2.2 | 6.4 | 126.2 | 117 | 60 | 57 | 13 | 31 | 90 | 5 | 0 | 0 | 2 | 9 | 3 | 3 | 3.72 |