| SP | Koufax, S.Koufax, Sandy † | Mets | L | 134.0 | 21 | 21 | 13 | 4 | 2.20 | .246 | 0.95 | 6.2 | 2.3 | 7.7 | 172.0 | 119 | 44 | 42 | 11 | 44 | 147 | 10 | 0 | 0 | 2 | 16 | 5 | 3 | 2.98 |
| SP | Alexander, P.Alexander, Pete † | Mets | R | 123.0 | 21 | 21 | 16 | 3 | 3.04 | .281 | 1.16 | 7.1 | 3.5 | 5.5 | 159.2 | 125 | 59 | 54 | 13 | 61 | 97 | 6 | 0 | 0 | 1 | 17 | 1 | 3 | 4.01 |
| SP | Verlander, J.Verlander, Justin † # | SPARTICISTS | R | 90.0 | 22 | 22 | 12 | 4 | 3.57 | .265 | 1.05 | 7.4 | 2.1 | 9.3 | 138.2 | 114 | 56 | 55 | 14 | 32 | 143 | 3 | 0 | 0 | 3 | 12 | 4 | 1 | 3.03 |
| SP | Leonard, D.Leonard, Dutch | Mets | L | 89.0 | 21 | 21 | 12 | 2 | 3.12 | .271 | 1.11 | 7.0 | 3.0 | 5.5 | 130.0 | 101 | 45 | 45 | 9 | 43 | 79 | 0 | 0 | 0 | 0 | 15 | 1 | 2 | 3.70 |
| SP | deGrom, J.deGrom, Jacob † $$ | Warriors | R | 89.0 | 22 | 22 | 11 | 8 | 2.90 | .263 | 1.07 | 7.7 | 2.0 | 8.9 | 155.0 | 132 | 56 | 50 | 20 | 34 | 154 | 1 | 0 | 0 | 1 | 16 | 0 | 0 | 3.35 |
| SP | Johnson, R.Johnson, Randy # | Blue Fish | L | 77.0 | 21 | 21 | 11 | 6 | 3.87 | .270 | 1.10 | 8.1 | 1.8 | 8.3 | 151.1 | 136 | 70 | 65 | 25 | 30 | 140 | 4 | 0 | 0 | 1 | 12 | 2 | 1 | 3.93 |