| CL | Rivera, M.Rivera, Mariano † | Tide | R | 162.0 | 71 | 0 | 11 | 5 | 2.93 | .248 | 0.94 | 6.8 | 1.7 | 9.0 | 73.2 | 55 | 25 | 24 | 7 | 14 | 73 | 0 | 40 | 5 | 0 | 0 | 4 | 1 | 2.99 |
| SP | Lincecum, T.Lincecum, Tim † | Otters | R | 147.0 | 34 | 34 | 17 | 9 | 3.00 | .276 | 1.12 | 7.4 | 2.7 | 8.9 | 236.2 | 195 | 79 | 79 | 19 | 70 | 234 | 7 | 0 | 0 | 2 | 26 | 5 | 8 | 3.02 |
| SP | Hernandez, F.Hernandez, Felix † # | Vikings | R | 144.0 | 34 | 34 | 19 | 10 | 3.53 | .276 | 1.10 | 7.2 | 2.7 | 7.0 | 254.2 | 204 | 101 | 100 | 31 | 77 | 198 | 9 | 0 | 0 | 3 | 19 | 10 | 3 | 4.06 |
| SP | Santana, J.Santana, Johan † | Tide | L | 137.0 | 34 | 34 | 18 | 9 | 3.42 | .286 | 1.18 | 8.1 | 2.5 | 10.1 | 236.2 | 213 | 91 | 90 | 29 | 66 | 265 | 1 | 0 | 0 | 1 | 21 | 6 | 7 | 3.27 |
| CL | Broxton, J.Broxton, Jonathan † | Amigos | R | 126.0 | 86 | 0 | 6 | 11 | 2.86 | .284 | 1.14 | 6.7 | 3.6 | 10.9 | 104.0 | 77 | 35 | 33 | 11 | 42 | 126 | 0 | 36 | 6 | 0 | 0 | 5 | 4 | 3.31 |
| SP | Schmidt, J.Schmidt, Jason | Ducks | R | 120.0 | 35 | 35 | 18 | 14 | 3.88 | .313 | 1.33 | 9.0 | 3.0 | 8.9 | 255.0 | 255 | 124 | 110 | 34 | 85 | 252 | 6 | 0 | 0 | 0 | 21 | 9 | 6 | 3.86 |
| SP | Martinez, P.Martinez, Pedro | Amigos | R | 114.0 | 33 | 33 | 15 | 8 | 3.74 | .296 | 1.21 | 7.8 | 3.1 | 9.7 | 221.2 | 191 | 98 | 92 | 26 | 77 | 238 | 5 | 0 | 0 | 1 | 22 | 11 | 3 | 3.57 |