| SP | Yamamoto, Y.Yamamoto, Yoshinobu † | Sharks | R | 88.0 | 22 | 22 | 11 | 8 | 2.71 | .274 | 1.08 | 6.3 | 3.5 | 9.8 | 139.2 | 97 | 43 | 42 | 9 | 54 | 151 | 1 | 0 | 0 | 1 | 13 | 7 | 6 | 2.99 |
| SP | Imanaga, S.Imanaga, Shota † | Cubs | L | 83.0 | 21 | 21 | 12 | 4 | 3.61 | .293 | 1.21 | 8.3 | 2.7 | 7.4 | 132.0 | 121 | 58 | 53 | 15 | 39 | 108 | 1 | 0 | 0 | 1 | 14 | 4 | 1 | 3.82 |
| CL | Svanson, M.Svanson, Matt † | Hot Rods | R | 81.0 | 46 | 0 | 3 | 5 | 2.50 | .260 | 1.01 | 6.1 | 3.1 | 11.7 | 50.1 | 34 | 16 | 14 | 1 | 17 | 65 | 0 | 24 | 2 | 0 | 0 | 2 | 0 | 1.80 |
| SP | Crochet, G.Crochet, Garrett † | Hot Rods | L | 76.0 | 21 | 21 | 10 | 4 | 3.53 | .288 | 1.12 | 8.0 | 2.0 | 11.1 | 130.0 | 116 | 51 | 51 | 18 | 29 | 160 | 0 | 0 | 0 | 0 | 13 | 13 | 2 | 3.31 |
| SP | deGrom, J.deGrom, Jacob † | Mets | R | 75.0 | 22 | 22 | 8 | 4 | 3.07 | .280 | 1.12 | 7.4 | 2.7 | 10.7 | 140.2 | 115 | 49 | 48 | 15 | 42 | 166 | 1 | 0 | 0 | 0 | 13 | 7 | 1 | 3.07 |