| CL | Leclerc, J.Leclerc, Jose † | Pythons | R | 136.0 | 68 | 0 | 2 | 6 | 2.08 | .262 | 1.04 | 5.7 | 3.7 | 11.0 | 69.1 | 44 | 16 | 16 | 2 | 28 | 84 | 0 | 44 | 1 | 0 | 0 | 2 | 0 | 2.25 |
| SP | Verlander, J.Verlander, Justin | Bombas | R | 131.0 | 36 | 36 | 17 | 12 | 3.43 | .284 | 1.16 | 8.2 | 2.2 | 9.9 | 257.1 | 235 | 99 | 98 | 25 | 64 | 282 | 3 | 0 | 0 | 0 | 22 | 7 | 2 | 2.90 |
| SP | Scherzer, M.Scherzer, Max † # | Frogs | R | 124.0 | 34 | 34 | 14 | 8 | 3.15 | .285 | 1.17 | 7.3 | 3.2 | 9.6 | 240.0 | 194 | 86 | 84 | 28 | 86 | 257 | 0 | 0 | 0 | 0 | 25 | 7 | 6 | 3.54 |
| SP | Fernandez, J.Fernandez, Jose † | Pythons | R | 123.0 | 36 | 36 | 17 | 8 | 3.52 | .305 | 1.29 | 7.9 | 3.8 | 9.6 | 219.2 | 192 | 93 | 86 | 30 | 92 | 233 | 0 | 0 | 0 | 0 | 23 | 5 | 1 | 3.98 |
| SP | Arrieta, J.Arrieta, Jake † | Bulldogs | R | 123.0 | 35 | 35 | 16 | 13 | 3.29 | .278 | 1.14 | 7.8 | 2.5 | 10.5 | 235.0 | 203 | 97 | 86 | 27 | 65 | 273 | 3 | 0 | 0 | 0 | 26 | 3 | 4 | 3.04 |
| SP | Bumgarner, M.Bumgarner, Madison | Suns | L | 119.0 | 37 | 37 | 20 | 10 | 4.49 | .327 | 1.44 | 9.7 | 3.3 | 9.8 | 242.1 | 261 | 123 | 121 | 32 | 89 | 263 | 3 | 0 | 0 | 2 | 18 | 4 | 4 | 3.70 |
| RP | Rodney, F.Rodney, Fernando † | Frogs | R | 111.5 | 76 | 0 | 12 | 0 | 2.39 | .269 | 1.09 | 7.0 | 2.9 | 10.2 | 101.2 | 79 | 29 | 27 | 9 | 32 | 114 | 0 | 7 | 4 | 0 | 0 | 1 | 4 | 2.88 |
| SP | Kershaw, C.Kershaw, Clayton | Butt Munchers | L | 111.0 | 36 | 36 | 16 | 9 | 4.12 | .301 | 1.25 | 9.5 | 1.8 | 9.8 | 236.0 | 248 | 110 | 108 | 29 | 46 | 256 | 4 | 0 | 0 | 1 | 19 | 11 | 10 | 3.15 |