| SP | deGrom, J.deGrom, Jacob † # | Reapers | R | 111.0 | 21 | 21 | 11 | 7 | 2.10 | .250 | 0.98 | 6.6 | 2.3 | 10.5 | 154.1 | 113 | 37 | 36 | 13 | 39 | 180 | 3 | 0 | 0 | 3 | 17 | 2 | 2 | 2.56 |
| SP | Hernandez, F.Hernandez, Felix † | Demons | R | 104.0 | 20 | 20 | 13 | 5 | 3.08 | .288 | 1.20 | 7.1 | 3.7 | 10.0 | 149.0 | 118 | 53 | 51 | 11 | 61 | 165 | 3 | 0 | 0 | 2 | 12 | 2 | 4 | 3.01 |
| SP | Kluber, C.Kluber, Corey † # | Eagles | R | 80.0 | 21 | 21 | 9 | 9 | 3.03 | .278 | 1.15 | 8.5 | 1.9 | 10.6 | 157.1 | 148 | 57 | 53 | 16 | 33 | 185 | 4 | 0 | 0 | 0 | 15 | 1 | 0 | 2.62 |
| SP | Greinke, Z.Greinke, Zack # | Crabs | R | 78.0 | 19 | 19 | 10 | 5 | 3.47 | .252 | 0.98 | 7.2 | 1.6 | 8.1 | 145.1 | 116 | 58 | 56 | 20 | 26 | 131 | 3 | 0 | 0 | 1 | 12 | 5 | 0 | 3.63 |
| SP | Darvish, Y.Darvish, Yu † # | Dukes | R | 76.0 | 20 | 20 | 11 | 3 | 3.93 | .281 | 1.14 | 7.1 | 3.1 | 10.8 | 121.1 | 96 | 54 | 53 | 15 | 42 | 145 | 1 | 0 | 0 | 0 | 11 | 4 | 3 | 3.36 |
| SP | Scherzer, M.Scherzer, Max | Bamboozler | R | 73.0 | 21 | 21 | 11 | 6 | 3.74 | .282 | 1.16 | 6.7 | 3.8 | 10.4 | 132.1 | 98 | 56 | 55 | 15 | 55 | 152 | 0 | 0 | 0 | 0 | 13 | 3 | 1 | 3.49 |
| RP | Sanchez, A.Sanchez, Aaron | Dukes | R | 70.5 | 55 | 0 | 3 | 0 | 1.50 | .239 | 0.92 | 5.1 | 3.2 | 6.5 | 90.0 | 51 | 15 | 15 | 2 | 32 | 65 | 0 | 7 | 2 | 0 | 0 | 2 | 1 | 2.98 |