| SP | Verlander, J.Verlander, Justin # $$ | Red Sox | R | 125.0 | 28 | 28 | 15 | 7 | 2.88 | .265 | 1.06 | 6.8 | 2.7 | 10.5 | 190.2 | 144 | 61 | 61 | 16 | 58 | 221 | 1 | 0 | 0 | 1 | 22 | 4 | 1 | 2.75 |
| SP | Buehler, W.Buehler, Walker | Cyclones | R | 120.0 | 28 | 28 | 17 | 5 | 3.34 | .301 | 1.27 | 8.2 | 3.3 | 8.8 | 172.2 | 156 | 66 | 64 | 14 | 64 | 169 | 0 | 0 | 0 | 0 | 16 | 3 | 1 | 3.26 |
| SP | Hernandez, F.Hernandez, Felix † # | Mustangs | R | 108.0 | 27 | 27 | 14 | 7 | 3.53 | .249 | 0.96 | 7.1 | 1.5 | 9.9 | 186.0 | 147 | 75 | 73 | 24 | 32 | 205 | 4 | 0 | 0 | 1 | 16 | 6 | 2 | 3.09 |
| CL | Kimbrel, C.Kimbrel, Craig † | Red Sox | R | 107.5 | 54 | 0 | 4 | 6 | 1.65 | .196 | 0.72 | 4.2 | 2.3 | 11.7 | 60.0 | 28 | 12 | 11 | 1 | 15 | 78 | 0 | 29 | 1 | 0 | 0 | 1 | 1 | 1.42 |
| SP | Foltynewicz, M.Foltynewicz, Michael | Stallions | R | 98.0 | 26 | 26 | 15 | 4 | 3.99 | .315 | 1.36 | 8.3 | 3.9 | 9.5 | 160.0 | 147 | 74 | 71 | 21 | 70 | 168 | 0 | 0 | 0 | 0 | 12 | 4 | 1 | 3.99 |