| SP | Steele, E.Steele, Elmer † | Bosox | R | 112.0 | 18 | 18 | 14 | 3 | 2.91 | .285 | 1.18 | 8.3 | 2.3 | 4.7 | 148.2 | 137 | 56 | 48 | 11 | 38 | 77 | 5 | 0 | 0 | 3 | 11 | 3 | 0 | 3.76 |
| SP | Richard, J.Richard, J.R. † | Astros | R | 105.0 | 18 | 18 | 12 | 3 | 2.44 | .255 | 0.99 | 5.7 | 3.2 | 7.6 | 136.2 | 86 | 39 | 37 | 6 | 49 | 115 | 2 | 0 | 0 | 2 | 14 | 5 | 2 | 3.07 |
| SP | Kershaw, C.Kershaw, Clayton † | Dodgers | L | 96.0 | 18 | 18 | 10 | 3 | 2.51 | .262 | 1.06 | 7.7 | 1.8 | 8.9 | 132.2 | 113 | 44 | 37 | 10 | 27 | 130 | 4 | 0 | 0 | 2 | 14 | 1 | 0 | 2.65 |
| SP | Verlander, J.Verlander, Justin | Astros | R | 82.0 | 19 | 19 | 10 | 3 | 3.22 | .287 | 1.17 | 7.5 | 3.1 | 8.6 | 128.2 | 107 | 47 | 46 | 10 | 44 | 122 | 2 | 0 | 0 | 1 | 12 | 4 | 0 | 3.23 |
| SP | Martinez, P.Martinez, Pedro † | Bosox | R | 74.0 | 19 | 19 | 9 | 6 | 3.76 | .256 | 1.01 | 6.9 | 2.2 | 9.3 | 153.0 | 117 | 64 | 64 | 21 | 37 | 158 | 6 | 0 | 0 | 1 | 9 | 4 | 3 | 3.52 |