| SP | Mathewson, C.Mathewson, Christy † $ | Classics | R | 181.0 | 34 | 34 | 19 | 9 | 2.61 | .251 | 0.99 | 7.1 | 1.8 | 4.9 | 272.0 | 216 | 91 | 79 | 22 | 53 | 147 | 16 | 0 | 0 | 4 | 25 | 4 | 4 | 3.60 |
| SP | Martinez, P.Martinez, Pedro $$ | Bearkats | R | 163.0 | 33 | 33 | 20 | 8 | 3.05 | .267 | 1.06 | 6.7 | 2.8 | 7.9 | 260.0 | 193 | 94 | 88 | 22 | 82 | 227 | 5 | 0 | 0 | 0 | 21 | 9 | 5 | 3.40 |
| SP | Gibson, B.Gibson, Bob † # | Bearkats | R | 152.0 | 34 | 34 | 19 | 9 | 3.25 | .266 | 1.07 | 7.6 | 2.1 | 6.1 | 271.2 | 228 | 105 | 98 | 23 | 64 | 183 | 7 | 0 | 0 | 1 | 24 | 3 | 1 | 3.49 |
| SP | deGrom, J.deGrom, Jacob † $ | CANNONFODDER | R | 151.0 | 34 | 34 | 17 | 7 | 2.65 | .262 | 1.06 | 7.4 | 2.1 | 9.6 | 227.2 | 187 | 73 | 67 | 22 | 54 | 243 | 1 | 0 | 0 | 0 | 27 | 1 | 0 | 2.85 |
| CL | Kimbrel, C.Kimbrel, Craig † | Bearkats | R | 149.5 | 62 | 0 | 0 | 2 | 1.67 | .223 | 0.83 | 4.3 | 3.2 | 9.3 | 59.1 | 28 | 12 | 11 | 4 | 21 | 61 | 0 | 53 | 5 | 0 | 0 | 2 | 2 | 2.98 |
| CL | Feliz, N.Feliz, Neftali † $ | Beezus | R | 148.0 | 72 | 0 | 7 | 6 | 3.12 | .289 | 1.21 | 6.5 | 4.4 | 10.2 | 83.2 | 60 | 31 | 29 | 6 | 41 | 94 | 0 | 42 | 4 | 0 | 0 | 1 | 0 | 3.19 |
| CL | Street, H.Street, Huston † $ | Storm | R | 141.0 | 76 | 0 | 6 | 7 | 2.89 | .272 | 1.11 | 6.6 | 3.4 | 7.7 | 81.0 | 59 | 27 | 26 | 8 | 31 | 69 | 0 | 42 | 4 | 0 | 0 | 1 | 2 | 3.77 |