| SP | Mathewson, C.Mathewson, Christy $$ | Classics | R | 103.0 | 21 | 21 | 13 | 6 | 2.98 | .266 | 1.08 | 7.7 | 1.9 | 3.8 | 157.0 | 135 | 58 | 52 | 13 | 34 | 66 | 7 | 0 | 0 | 3 | 13 | 2 | 2 | 3.92 |
| SP | Maddux, G.Maddux, Greg # $ | Bombers | R | 100.0 | 20 | 20 | 13 | 6 | 2.74 | .261 | 1.06 | 7.6 | 2.0 | 5.8 | 141.1 | 119 | 44 | 43 | 18 | 31 | 91 | 4 | 0 | 0 | 1 | 15 | 0 | 1 | 4.03 |
| SP | Verlander, J.Verlander, Justin † $$ | Pinetar Heroes | R | 93.0 | 22 | 22 | 11 | 4 | 3.10 | .275 | 1.12 | 7.7 | 2.3 | 8.9 | 151.0 | 130 | 56 | 52 | 15 | 39 | 150 | 2 | 0 | 0 | 1 | 14 | 3 | 2 | 3.14 |
| CL | Jansen, K.Jansen, Kenley † | Apocalypse | R | 91.0 | 44 | 0 | 5 | 2 | 3.48 | .279 | 1.16 | 7.2 | 3.3 | 8.8 | 44.0 | 35 | 19 | 17 | 5 | 16 | 43 | 0 | 26 | 5 | 0 | 0 | 0 | 0 | 3.61 |
| SP | Snell, B.Snell, Blake † $ | Classics | L | 85.0 | 20 | 20 | 11 | 3 | 3.12 | .259 | 1.05 | 6.1 | 3.3 | 8.1 | 130.0 | 88 | 46 | 45 | 10 | 48 | 117 | 0 | 0 | 0 | 0 | 15 | 0 | 4 | 3.31 |
| SP | Alexander, P.Alexander, Pete # | Skeletons | R | 83.0 | 22 | 22 | 10 | 9 | 3.36 | .262 | 1.06 | 8.1 | 1.5 | 5.4 | 168.2 | 151 | 71 | 63 | 16 | 28 | 100 | 11 | 0 | 0 | 2 | 14 | 1 | 0 | 3.57 |
| SP | Gibson, B.Gibson, Bob † $ | Warriors | R | 83.0 | 20 | 20 | 10 | 10 | 3.27 | .283 | 1.16 | 7.5 | 2.9 | 5.4 | 165.0 | 138 | 63 | 60 | 17 | 53 | 99 | 12 | 0 | 0 | 2 | 12 | 4 | 1 | 4.18 |
| SP | Koufax, S.Koufax, Sandy † $ | North | L | 82.0 | 22 | 22 | 11 | 7 | 3.57 | .297 | 1.26 | 8.7 | 2.7 | 6.5 | 156.1 | 151 | 63 | 62 | 18 | 46 | 113 | 5 | 0 | 0 | 3 | 12 | 1 | 3 | 3.96 |
| SP | deGrom, J.deGrom, Jacob $ | Warriors | R | 80.0 | 22 | 22 | 11 | 9 | 3.03 | .270 | 1.10 | 7.4 | 2.5 | 9.4 | 145.2 | 120 | 54 | 49 | 17 | 40 | 152 | 0 | 0 | 0 | 0 | 14 | 2 | 0 | 3.30 |