| SP | Hernandez, F.Hernandez, Felix † # | Ducks | R | 145.0 | 30 | 30 | 19 | 9 | 3.26 | .278 | 1.14 | 8.0 | 2.3 | 8.4 | 218.0 | 194 | 82 | 79 | 18 | 55 | 203 | 5 | 0 | 0 | 5 | 20 | 3 | 9 | 3.01 |
| SP | Kershaw, C.Kershaw, Clayton † | Raging Bulls | L | 123.0 | 30 | 30 | 15 | 9 | 3.30 | .268 | 1.06 | 8.1 | 1.4 | 9.8 | 218.0 | 196 | 86 | 80 | 32 | 34 | 238 | 4 | 0 | 0 | 2 | 22 | 9 | 3 | 3.32 |
| SP | deGrom, J.deGrom, Jacob † | Aces | R | 121.0 | 31 | 31 | 16 | 7 | 3.54 | .294 | 1.22 | 8.2 | 2.8 | 9.4 | 213.2 | 195 | 87 | 84 | 27 | 66 | 222 | 2 | 0 | 0 | 1 | 21 | 6 | 3 | 3.58 |
| CL | Sanchez, A.Sanchez, Aaron † | Raging Bulls | R | 115.0 | 65 | 0 | 7 | 10 | 2.57 | .233 | 0.88 | 5.0 | 2.9 | 5.1 | 77.0 | 43 | 23 | 22 | 9 | 25 | 44 | 0 | 32 | 3 | 0 | 0 | 2 | 3 | 4.43 |
| SP | Kluber, C.Kluber, Corey † | Brawlers | R | 110.0 | 31 | 31 | 14 | 10 | 3.40 | .278 | 1.12 | 8.0 | 2.2 | 9.4 | 209.0 | 185 | 85 | 79 | 28 | 50 | 219 | 5 | 0 | 0 | 0 | 22 | 6 | 4 | 3.45 |
| CL | Chapman, A.Chapman, Aroldis † | Aces | L | 101.5 | 68 | 0 | 5 | 9 | 4.30 | .281 | 1.15 | 5.7 | 4.7 | 10.7 | 73.1 | 46 | 35 | 35 | 8 | 38 | 87 | 0 | 35 | 5 | 0 | 0 | 2 | 0 | 3.68 |
| CL | Uehara, K.Uehara, Koji † $$ | Braves | R | 101.0 | 55 | 0 | 2 | 6 | 2.34 | .226 | 0.86 | 5.5 | 2.4 | 11.4 | 61.2 | 37 | 16 | 16 | 4 | 16 | 77 | 0 | 34 | 5 | 0 | 0 | 1 | 1 | 2.16 |