| SP | Tanana, F.Tanana, Frank † # | Halos | L | 118.0 | 20 | 20 | 14 | 4 | 3.26 | .261 | 1.05 | 7.2 | 2.3 | 5.8 | 162.2 | 130 | 59 | 59 | 11 | 41 | 104 | 11 | 0 | 0 | 6 | 12 | 1 | 1 | 3.38 |
| SP | McLain, D.McLain, Denny † # | Tigers | R | 116.0 | 20 | 19 | 12 | 3 | 2.70 | .245 | 0.96 | 6.9 | 1.8 | 5.9 | 146.2 | 112 | 51 | 44 | 10 | 29 | 96 | 12 | 0 | 0 | 5 | 13 | 2 | 2 | 3.21 |
| RP | Holton, T.Holton, Tyler † | Tigers | L | 103.5 | 49 | 0 | 16 | 2 | 3.04 | .292 | 1.23 | 7.4 | 3.6 | 6.5 | 80.0 | 66 | 28 | 27 | 6 | 32 | 58 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.76 |
| SP | Miller, B.Miller, Bryce † # | Mariners 4 | R | 103.0 | 19 | 19 | 12 | 0 | 2.47 | .258 | 1.04 | 7.0 | 2.3 | 8.3 | 123.2 | 96 | 36 | 34 | 8 | 32 | 114 | 0 | 0 | 0 | 0 | 17 | 1 | 3 | 2.80 |
| SP | Wheeler, Z.Wheeler, Zack † | Phillies | R | 102.0 | 21 | 21 | 13 | 5 | 2.79 | .266 | 1.08 | 7.2 | 2.5 | 9.4 | 145.0 | 116 | 47 | 45 | 13 | 41 | 152 | 0 | 0 | 0 | 0 | 15 | 1 | 0 | 2.94 |
| SP | Skubal, T.Skubal, Tarik † | Tigers | L | 94.0 | 20 | 20 | 11 | 3 | 2.87 | .279 | 1.16 | 7.9 | 2.5 | 9.2 | 135.0 | 119 | 45 | 43 | 12 | 37 | 138 | 1 | 0 | 0 | 1 | 15 | 1 | 0 | 2.96 |