| SP | Kershaw, C.Kershaw, Clayton † | Classics | L | 144.0 | 31 | 31 | 19 | 7 | 3.26 | .272 | 1.10 | 7.7 | 2.2 | 7.3 | 223.2 | 192 | 86 | 81 | 19 | 55 | 180 | 4 | 0 | 0 | 2 | 17 | 4 | 5 | 3.29 |
| SP | Koufax, S.Koufax, Sandy † | Rock City | L | 139.0 | 31 | 31 | 15 | 11 | 2.84 | .284 | 1.17 | 7.6 | 3.0 | 8.7 | 243.2 | 205 | 83 | 77 | 19 | 81 | 234 | 7 | 0 | 0 | 2 | 22 | 4 | 4 | 3.14 |
| RP | Feliz, N.Feliz, Neftali † | Sloths | R | 117.5 | 83 | 0 | 8 | 2 | 1.71 | .266 | 1.06 | 6.1 | 3.4 | 9.1 | 126.0 | 86 | 27 | 24 | 6 | 47 | 127 | 0 | 11 | 2 | 0 | 0 | 4 | 0 | 2.82 |
| SP | Leonard, D.Leonard, Dutch | Kitty | L | 114.0 | 30 | 30 | 15 | 6 | 2.99 | .275 | 1.11 | 6.4 | 3.6 | 4.4 | 192.2 | 137 | 67 | 64 | 9 | 76 | 94 | 1 | 0 | 0 | 1 | 21 | 6 | 2 | 3.91 |
| SP | deGrom, J.deGrom, Jacob # $ | Warriors | R | 111.0 | 31 | 31 | 13 | 7 | 3.21 | .260 | 1.03 | 7.2 | 2.1 | 10.0 | 207.1 | 166 | 77 | 74 | 25 | 48 | 231 | 0 | 0 | 0 | 0 | 21 | 5 | 0 | 3.11 |
| SP | Fernandez, J.Fernandez, Jose | Classics | R | 108.0 | 29 | 29 | 14 | 4 | 3.47 | .290 | 1.23 | 7.5 | 3.5 | 7.6 | 184.1 | 154 | 79 | 71 | 21 | 72 | 155 | 2 | 0 | 0 | 1 | 16 | 0 | 5 | 3.97 |
| SP | Greinke, Z.Greinke, Zack $ | Warriors | R | 106.0 | 30 | 30 | 14 | 9 | 3.54 | .272 | 1.09 | 7.4 | 2.4 | 5.3 | 221.1 | 182 | 90 | 87 | 28 | 60 | 130 | 7 | 0 | 0 | 2 | 17 | 6 | 4 | 4.37 |