| SP | Chamberlain, E.Chamberlain, Elton † | Cardinals | R | 146.0 | 24 | 24 | 16 | 6 | 2.57 | .267 | 1.08 | 6.2 | 3.6 | 5.9 | 199.1 | 137 | 66 | 57 | 15 | 79 | 130 | 12 | 0 | 0 | 3 | 17 | 2 | 0 | 3.89 |
| SP | Flaherty, J.Flaherty, Jack † | Cardinals | R | 129.0 | 23 | 23 | 15 | 1 | 2.52 | .256 | 1.01 | 6.5 | 2.6 | 9.2 | 157.1 | 113 | 45 | 44 | 8 | 46 | 160 | 0 | 0 | 0 | 0 | 20 | 3 | 3 | 2.56 |
| SP | Arrieta, J.Arrieta, Jake † | Cubs | R | 115.0 | 23 | 23 | 14 | 3 | 3.17 | .297 | 1.26 | 9.4 | 2.0 | 8.9 | 167.2 | 174 | 69 | 59 | 13 | 37 | 165 | 5 | 0 | 0 | 0 | 16 | 2 | 2 | 2.74 |
| SP | Richard, J.Richard, J.R. # | Astr6s | R | 108.0 | 22 | 22 | 13 | 4 | 2.96 | .267 | 1.08 | 6.5 | 3.2 | 7.7 | 158.0 | 114 | 55 | 52 | 12 | 57 | 135 | 4 | 0 | 0 | 1 | 17 | 2 | 2 | 3.40 |
| RP | Gossage, R.Gossage, Rich † | YaNGks 1007 WAR | R | 96.5 | 65 | 0 | 11 | 1 | 2.31 | .269 | 1.09 | 6.3 | 3.6 | 9.8 | 81.2 | 57 | 23 | 21 | 5 | 32 | 88 | 0 | 5 | 0 | 0 | 0 | 1 | 5 | 2.85 |
| SP | Marichal, J.Marichal, Juan | Gaints | R | 96.0 | 24 | 24 | 12 | 7 | 3.66 | .281 | 1.14 | 8.0 | 2.3 | 6.1 | 187.0 | 166 | 76 | 76 | 20 | 48 | 126 | 12 | 0 | 0 | 1 | 14 | 5 | 2 | 3.89 |
| RP | Kimbrel, C.Kimbrel, Craig † | Cubs | R | 94.0 | 65 | 0 | 15 | 2 | 3.26 | .296 | 1.21 | 4.5 | 6.4 | 9.3 | 80.0 | 40 | 31 | 29 | 5 | 57 | 83 | 0 | 2 | 3 | 0 | 0 | 4 | 1 | 4.03 |