| SP | Oswalt, R.Oswalt, Roy >> | 33 | 2010 | R | 100 | 13 | 13 | 2.76 | .252 | .280 | 1.03 | 6.9 | 2.3 | 8.2 | 211 | 162 | 19 | 55 | 193 | 2 | 0 | 2 | 113 | 18 | C |
| SP | Buehrle, M.Buehrle, Mark >> | 31 | 2010 | L | 24 | 13 | 13 | 4.28 | .316 | .340 | 1.40 | 10.5 | 2.1 | 4.2 | 210 | 246 | 17 | 49 | 99 | 3 | 0 | 3 | 112 | 14 | C |
| SP | Blackburn, N.Blackburn, Nick >> | 28 | 2010 | R | 16 | 10 | 12 | 5.42 | .322 | .350 | 1.45 | 10.8 | 2.2 | 3.8 | 161 | 194 | 25 | 40 | 68 | 1 | 0 | 3 | 102 | 14 | C |
| SP | Talbot, M.Talbot, Mitch >> | 27 | 2010 | R | 25 | 10 | 13 | 4.41 | .328 | .360 | 1.50 | 9.6 | 3.9 | 5.0 | 159 | 169 | 13 | 69 | 88 | 1 | 0 | 3 | 101 | 15 | C |
| SP | Burnett, A.Burnett, A.J. >> | 33 | 2010 | R | 23 | 10 | 15 | 5.26 | .332 | .360 | 1.52 | 9.9 | 3.8 | 7.0 | 186 | 204 | 25 | 78 | 145 | 1 | 0 | 16 | 100 | 17 | C |
| SP | Maholm, P.Maholm, Paul >> | 28 | 2010 | L | 10 | 9 | 15 | 5.10 | .339 | .370 | 1.57 | 11.1 | 3.0 | 5.0 | 185 | 228 | 15 | 62 | 102 | 1 | 0 | 2 | 102 | 15 | C |
| SP | Saunders, J.Saunders, Joe >> | 29 | 2010 | L | 21 | 9 | 17 | 4.47 | .323 | .350 | 1.46 | 10.3 | 2.8 | 5.1 | 203 | 232 | 25 | 64 | 114 | 3 | 0 | 6 | 109 | 15 | C |
| SP | Kazmir, S.Kazmir, Scott >> | 26 | 2010 | L | 20 | 9 | 15 | 5.94 | .340 | .370 | 1.58 | 9.5 | 4.7 | 5.6 | 150 | 158 | 25 | 79 | 93 | 0 | 0 | 6 | 95 | 15 | C |
| SP | Davies, K.Davies, Kyle >> | 27 | 2010 | R | 17 | 8 | 12 | 5.34 | .338 | .370 | 1.56 | 10.1 | 3.9 | 6.2 | 183 | 206 | 20 | 80 | 126 | 1 | 0 | 5 | 101 | 16 | C |
| SP | Lannan, J.Lannan, John >> | 26 | 2010 | L | 9 | 8 | 8 | 4.65 | .338 | .370 | 1.57 | 11.0 | 3.1 | 4.5 | 143 | 175 | 14 | 49 | 71 | 0 | 0 | 1 | 101 | 14 | C |
| SP | Leake, M.Leake, Mike >> | 22 | 2010 | R | 19 | 8 | 4 | 4.23 | .328 | .360 | 1.50 | 10.3 | 3.2 | 5.9 | 138 | 158 | 19 | 49 | 91 | 0 | 0 | 2 | 102 | 16 | C |
| SP | Duke, Z.Duke, Zach >> | 27 | 2010 | L | 5 | 8 | 15 | 5.72 | .351 | .380 | 1.65 | 12.0 | 2.9 | 5.4 | 159 | 212 | 25 | 51 | 96 | 0 | 0 | 4 | 97 | 15 | C |
| SP | Bush, D.Bush, David >> | 31 | 2010 | R | 18 | 8 | 13 | 4.54 | .331 | .360 | 1.51 | 10.2 | 3.4 | 5.5 | 174 | 198 | 28 | 65 | 107 | 0 | 0 | 1 | 96 | 15 | C |
| SP | Bergesen, B.Bergesen, Brad >> | 24 | 2010 | R | 22 | 8 | 12 | 4.98 | .319 | .350 | 1.44 | 10.2 | 2.7 | 4.3 | 170 | 193 | 26 | 51 | 81 | 2 | 0 | 0 | 100 | 14 | C |
| SP | Bannister, B.Bannister, Brian >> | 29 | 2010 | R | 8 | 7 | 12 | 6.34 | .347 | .380 | 1.64 | 11.2 | 3.5 | 5.5 | 127 | 158 | 23 | 50 | 77 | 0 | 0 | 10 | 94 | 15 | C |
| SP | Feldman, S.Feldman, Scott >> | 27 | 2010 | R | 7 | 7 | 11 | 5.48 | .343 | .370 | 1.60 | 11.6 | 2.9 | 4.8 | 141 | 181 | 18 | 45 | 75 | 0 | 0 | 11 | 87 | 15 | C |
| SP | Lopez, R.Lopez, Rodrigo >> | 35 | 2010 | R | 28 | 7 | 16 | 5.00 | .317 | .350 | 1.42 | 10.2 | 2.5 | 5.2 | 200 | 227 | 37 | 56 | 116 | 0 | 0 | 2 | 107 | 15 | C |
| SP | Cook, A.Cook, Aaron >> | 31 | 2010 | R | 10 | 6 | 8 | 5.08 | .337 | .370 | 1.57 | 10.4 | 3.7 | 4.4 | 127 | 147 | 11 | 52 | 62 | 2 | 0 | 3 | 98 | 14 | C |
| SP | Harang, A.Harang, Aaron >> | 32 | 2010 | R | 11 | 6 | 7 | 5.32 | .340 | .370 | 1.59 | 11.3 | 3.1 | 6.6 | 111 | 139 | 16 | 38 | 82 | 0 | 0 | 9 | 90 | 16 | C |
| SP | Robertson, N.Robertson, Nate >> | 33 | 2010 | L | 14 | 6 | 8 | 5.95 | .334 | .370 | 1.55 | 10.2 | 3.7 | 5.6 | 101 | 115 | 12 | 42 | 63 | 0 | 0 | 2 | 86 | 15 | C |
| SP | Arrieta, J.Arrieta, Jake >> | 24 | 2010 | R | 20 | 6 | 6 | 4.66 | .332 | .360 | 1.54 | 9.5 | 4.3 | 4.7 | 100 | 106 | 9 | 48 | 52 | 0 | 0 | 5 | 98 | 14 | C |
| SP | Atilano, L.Atilano, Luis >> | 25 | 2010 | R | 14 | 6 | 7 | 5.15 | .326 | .360 | 1.51 | 10.2 | 3.4 | 4.2 | 85 | 96 | 11 | 32 | 40 | 0 | 0 | 1 | 94 | 14 | C |
| SP | Masterson, J.Masterson, Justin >> | 25 | 2010 | R | 26 | 6 | 13 | 4.70 | .329 | .360 | 1.50 | 9.9 | 3.7 | 7.0 | 180 | 197 | 14 | 73 | 140 | 1 | 0 | 12 | 94 | 17 | C |
| SP | Beckett, J.Beckett, Josh >> | 30 | 2010 | R | 19 | 6 | 6 | 5.78 | .334 | .360 | 1.54 | 10.7 | 3.2 | 8.2 | 127 | 151 | 20 | 45 | 116 | 0 | 0 | 3 | 107 | 18 | C |
| SP | Stammen, C.Stammen, Craig >> | 26 | 2010 | R | 18 | 4 | 4 | 5.13 | .328 | .360 | 1.50 | 10.6 | 2.9 | 6.0 | 128 | 151 | 13 | 41 | 85 | 0 | 0 | 3 | 66 | 16 | C |
| SP | O'Sullivan, S.O'Sullivan, Sean >> | 22 | 2010 | R | 25 | 4 | 6 | 5.49 | .318 | .350 | 1.46 | 9.8 | 3.4 | 4.7 | 83 | 90 | 15 | 31 | 43 | 0 | 0 | 4 | 78 | 14 | C |
| SP | Burres, B.Burres, Brian >> | 29 | 2010 | L | 17 | 4 | 5 | 4.99 | .329 | .360 | 1.53 | 9.9 | 3.9 | 5.1 | 79 | 87 | 9 | 34 | 45 | 0 | 0 | 3 | 71 | 15 | C |
| SP | Olsen, S.Olsen, Scott >> | 26 | 2010 | L | 21 | 4 | 8 | 5.56 | .322 | .360 | 1.48 | 10.3 | 3.0 | 5.9 | 81 | 93 | 10 | 27 | 53 | 0 | 0 | 0 | 85 | 15 | C |
| SP | Millwood, K.Millwood, Kevin >> | 36 | 2010 | R | 15 | 4 | 16 | 5.10 | .332 | .360 | 1.52 | 10.6 | 3.1 | 6.3 | 190 | 223 | 30 | 65 | 132 | 1 | 0 | 7 | 108 | 16 | C |
| SP | Gomez, J.Gomez, Jeanmar >> | 22 | 2010 | R | 6 | 4 | 5 | 4.68 | .344 | .380 | 1.67 | 11.5 | 3.5 | 5.4 | 57 | 73 | 7 | 22 | 34 | 0 | 0 | 1 | 92 | 15 | C |
| SP | Lohse, K.Lohse, Kyle >> | 32 | 2010 | R | 3 | 4 | 8 | 6.55 | .364 | .400 | 1.78 | 12.6 | 3.4 | 5.3 | 92 | 129 | 9 | 35 | 54 | 0 | 0 | 1 | 91 | 15 | C |
| SP | Rzepczynski, M.Rzepczynski, Marc >> | 24 | 2010 | L | 16 | 4 | 4 | 4.95 | .339 | .380 | 1.62 | 10.3 | 4.3 | 8.1 | 63 | 72 | 8 | 30 | 57 | 0 | 0 | 4 | 80 | 18 | C |
| SP | Minor, M.Minor, Mike >> | 22 | 2010 | L | 13 | 3 | 2 | 5.98 | .330 | .370 | 1.60 | 11.9 | 2.5 | 9.7 | 40 | 53 | 6 | 11 | 43 | 0 | 0 | 0 | 80 | 20 | C |
| SP | Eveland, D.Eveland, Dana >> | 27 | 2010 | L | 1 | 3 | 5 | 6.79 | .377 | .420 | 1.93 | 12.0 | 5.3 | 4.0 | 54 | 72 | 4 | 32 | 24 | 0 | 0 | 4 | 80 | 14 | C |
| SP | Suppan, J.Suppan, Jeff >> | 35 | 2010 | R | 4 | 3 | 8 | 5.06 | .348 | .380 | 1.65 | 11.6 | 3.3 | 4.5 | 101 | 130 | 13 | 37 | 51 | 0 | 0 | 4 | 61 | 14 | C |
| SP | Karstens, J.Karstens, Jeff >> | 28 | 2010 | R | 24 | 3 | 10 | 4.92 | .315 | .350 | 1.42 | 10.8 | 2.0 | 5.3 | 122 | 146 | 21 | 27 | 72 | 0 | 0 | 0 | 84 | 15 | C |
| SP | Willis, D.Willis, Dontrelle >> | 28 | 2010 | L | 12 | 2 | 3 | 5.62 | .384 | .420 | 1.97 | 10.0 | 7.8 | 6.5 | 65 | 72 | 6 | 56 | 47 | 0 | 0 | 8 | 78 | 16 | C |
| SP | Huff, D.Huff, David >> | 25 | 2010 | L | 4 | 2 | 11 | 6.21 | .353 | .390 | 1.71 | 11.5 | 3.9 | 4.2 | 79 | 101 | 14 | 34 | 37 | 1 | 0 | 2 | 94 | 14 | C |
| SP | Morton, C.Morton, Charlie >> | 27 | 2010 | R | 6 | 2 | 12 | 7.57 | .358 | .390 | 1.75 | 12.8 | 3.0 | 6.7 | 79 | 112 | 15 | 26 | 59 | 0 | 0 | 5 | 83 | 17 | C |
| SP | Marquis, J.Marquis, Jason >> | 32 | 2010 | R | 3 | 2 | 9 | 6.60 | .352 | .390 | 1.72 | 11.8 | 3.7 | 4.8 | 58 | 76 | 9 | 24 | 31 | 0 | 0 | 1 | 80 | 15 | C |
| SP | Kawakami, K.Kawakami, Kenshin >> | 35 | 2010 | R | 22 | 1 | 10 | 5.15 | .324 | .360 | 1.49 | 10.1 | 3.3 | 6.1 | 87 | 98 | 10 | 32 | 59 | 0 | 0 | 4 | 86 | 16 | C |
| SP | Miller, A.Miller, Andrew >> | 25 | 2010 | L | 5 | 1 | 5 | 8.54 | .421 | .470 | 2.41 | 14.3 | 7.3 | 7.9 | 32 | 51 | 6 | 26 | 28 | 0 | 0 | 5 | 64 | 19 | C |
| SP | Litsch, J.Litsch, Jesse >> | 25 | 2010 | R | 15 | 1 | 5 | 5.79 | .315 | .360 | 1.48 | 10.4 | 2.9 | 3.1 | 46 | 53 | 7 | 15 | 16 | 0 | 0 | 1 | 91 | 13 | C |
| SP | Lincoln, B.Lincoln, Brad >> | 25 | 2010 | R | 9 | 1 | 4 | 6.66 | .328 | .370 | 1.56 | 11.4 | 2.6 | 4.3 | 52 | 66 | 9 | 15 | 25 | 0 | 0 | 1 | 84 | 15 | C |
| SP | Paulino, F.Paulino, Felipe >> | 27 | 2010 | R | 31 | 1 | 9 | 5.11 | .333 | .370 | 1.55 | 9.4 | 4.5 | 8.2 | 91 | 95 | 4 | 46 | 83 | 0 | 0 | 6 | 85 | 18 | C |
| SP | Maine, J.Maine, John >> | 29 | 2010 | R | 13 | 1 | 3 | 6.13 | .362 | .410 | 1.85 | 10.8 | 5.8 | 9.0 | 39 | 47 | 8 | 25 | 39 | 0 | 0 | 3 | 78 | 19 | C |
| SP | Rowland-Smith, R.Rowland-Smith, Ryan >> | 27 | 2010 | L | 2 | 1 | 10 | 6.75 | .354 | .390 | 1.70 | 11.6 | 3.6 | 4.0 | 109 | 141 | 25 | 44 | 49 | 0 | 0 | 7 | 73 | 14 | C |
| SP | Smith, G.Smith, Greg >> | 27 | 2010 | L | 8 | 1 | 2 | 6.23 | .365 | .410 | 1.87 | 11.3 | 5.5 | 7.2 | 39 | 49 | 8 | 24 | 31 | 0 | 0 | 1 | 87 | 17 | C |
| SP | Davis, D.Davis, Doug >> | 35 | 2010 | L | 7 | 1 | 4 | 7.51 | .380 | .430 | 2.00 | 13.0 | 5.0 | 8.1 | 38 | 55 | 6 | 21 | 34 | 0 | 0 | 3 | 85 | 18 | C |
| SP | Snell, I.Snell, Ian >> | 29 | 2010 | R | 2 | 0 | 5 | 6.41 | .365 | .410 | 1.85 | 11.7 | 4.9 | 5.1 | 46 | 60 | 10 | 25 | 26 | 0 | 0 | 3 | 69 | 15 | C |
| SP | Haeger, C.Haeger, Charlie >> | 27 | 2010 | R | 11 | 0 | 4 | 8.40 | .383 | .430 | 2.07 | 10.8 | 7.8 | 9.0 | 30 | 36 | 4 | 26 | 30 | 0 | 0 | 4 | 61 | 20 | C |