| RP | Nicasio, J.Nicasio, Juan >> | 29 | 2016 | R | 24 | 10 | 7 | 4.50 | .308 | .350 | 1.37 | 8.9 | 3.4 | 10.5 | 118 | 117 | 15 | 45 | 138 | 0 | 0 | 3 | 43 | +0.42 | C |
| RP | Warren, A.Warren, Adam >> | 28 | 2016 | R | 23 | 7 | 4 | 4.68 | .300 | .340 | 1.35 | 8.2 | 4.0 | 7.2 | 65 | 59 | 11 | 29 | 52 | 0 | 0 | 3 | 23 | -0.41 | C |
| RP | Ramirez, E.Ramirez, Erasmo >> | 26 | 2016 | R | 25 | 7 | 11 | 3.77 | .293 | .330 | 1.29 | 9.0 | 2.6 | 6.3 | 90 | 90 | 14 | 26 | 63 | 0 | 2 | 7 | 28 | +0.9 | C |
| RP | Robles, H.Robles, Hansel >> | 25 | 2016 | R | 33 | 6 | 4 | 3.48 | .303 | .340 | 1.36 | 8.1 | 4.2 | 9.9 | 77 | 69 | 7 | 36 | 85 | 0 | 1 | 3 | 23 | +0.83 | C |
| RP | Madson, R.Madson, Ryan >> | 36 | 2016 | R | 26 | 6 | 7 | 3.62 | .291 | .330 | 1.30 | 8.9 | 2.8 | 6.9 | 64 | 63 | 7 | 20 | 49 | 0 | 30 | 4 | 23 | +1.31 | C |
| RP | Norris, B.Norris, Bud >> | 31 | 2016 | R | 15 | 6 | 10 | 5.10 | .321 | .360 | 1.46 | 9.2 | 3.9 | 8.1 | 113 | 116 | 14 | 49 | 102 | 0 | 0 | 7 | 59 | -0.02 | C |
| RP | Axford, J.Axford, John >> | 33 | 2016 | R | 16 | 6 | 4 | 3.97 | .317 | .360 | 1.46 | 9.0 | 4.2 | 8.3 | 65 | 65 | 6 | 30 | 60 | 0 | 3 | 4 | 23 | +0.88 | C |
| RP | Dunn, M.Dunn, Mike >> | 31 | 2016 | L | 30 | 6 | 1 | 3.40 | .284 | .330 | 1.29 | 9.2 | 2.4 | 8.1 | 42 | 43 | 5 | 11 | 38 | 0 | 0 | 2 | 23 | +0.6 | C |
| RP | Robertson, D.Robertson, David >> | 31 | 2016 | R | 37 | 5 | 3 | 3.47 | .302 | .350 | 1.37 | 7.7 | 4.6 | 10.9 | 62 | 53 | 6 | 32 | 75 | 0 | 37 | 1 | 23 | +1.22 | C |
| RP | Soria, J.Soria, Joakim >> | 32 | 2016 | R | 12 | 5 | 8 | 4.05 | .318 | .360 | 1.47 | 9.5 | 3.7 | 9.3 | 66 | 70 | 10 | 27 | 68 | 0 | 1 | 2 | 23 | +0.39 | C |
| RP | Storen, D.Storen, Drew >> | 28 | 2016 | R | 19 | 4 | 3 | 5.23 | .297 | .340 | 1.35 | 9.9 | 2.3 | 8.5 | 51 | 56 | 7 | 13 | 48 | 0 | 3 | 0 | 23 | -0.26 | C |
| RP | Cahill, T.Cahill, Trevor >> | 28 | 2016 | R | 47 | 4 | 4 | 2.74 | .291 | .330 | 1.29 | 6.8 | 4.8 | 9.1 | 65 | 49 | 7 | 35 | 66 | 0 | 0 | 3 | 26 | +0.96 | C |
| RP | Clippard, T.Clippard, Tyler >> | 31 | 2016 | R | 45 | 4 | 6 | 3.57 | .287 | .330 | 1.27 | 7.7 | 3.7 | 10.3 | 63 | 54 | 10 | 26 | 72 | 0 | 3 | 5 | 23 | +1.02 | C |
| RP | Ziegler, B.Ziegler, Brad >> | 37 | 2016 | R | 20 | 4 | 7 | 2.25 | .303 | .350 | 1.37 | 8.9 | 3.4 | 7.7 | 68 | 67 | 2 | 26 | 58 | 0 | 22 | 1 | 23 | +2.19 | C |
| RP | Wilson, J.Wilson, Justin >> | 28 | 2016 | L | 27 | 4 | 5 | 4.14 | .298 | .340 | 1.34 | 9.5 | 2.6 | 10.1 | 58 | 61 | 6 | 17 | 65 | 0 | 1 | 4 | 23 | +0.53 | C |
| RP | Dyson, S.Dyson, Sam >> | 28 | 2016 | R | 42 | 3 | 2 | 2.43 | .281 | .320 | 1.23 | 8.1 | 3.0 | 7.1 | 70 | 63 | 5 | 23 | 55 | 0 | 38 | 3 | 23 | +2.86 | C |
| RP | Richard, C.Richard, Clayton >> | 33 | 2016 | L | 4 | 3 | 4 | 3.33 | .347 | .390 | 1.67 | 10.9 | 4.2 | 5.5 | 67 | 81 | 4 | 31 | 41 | 0 | 1 | 3 | 36 | +0.43 | C |
| RP | Collmenter, J.Collmenter, Josh >> | 30 | 2016 | R | 40 | 3 | 0 | 3.70 | .281 | .330 | 1.27 | 7.9 | 3.5 | 7.2 | 41 | 36 | 7 | 16 | 33 | 0 | 0 | 0 | 43 | +0.77 | C |
| RP | Petit, Y.Petit, Yusmeiro >> | 32 | 2016 | R | 20 | 3 | 5 | 4.50 | .295 | .340 | 1.32 | 9.7 | 2.2 | 7.1 | 62 | 67 | 12 | 15 | 49 | 0 | 1 | 3 | 33 | +0.19 | C |
| RP | Hernandez, D.Hernandez, David >> | 31 | 2016 | R | 14 | 3 | 4 | 3.84 | .325 | .370 | 1.51 | 9.6 | 4.0 | 10.0 | 72 | 77 | 11 | 32 | 80 | 0 | 1 | 6 | 23 | +0.92 | C |
| RP | Hudson, D.Hudson, Daniel >> | 29 | 2016 | R | 14 | 3 | 2 | 5.22 | .314 | .360 | 1.45 | 9.8 | 3.3 | 8.7 | 60 | 65 | 6 | 22 | 58 | 0 | 5 | 5 | 23 | -0.58 | C |
| RP | Bastardo, A.Bastardo, Antonio >> | 31 | 2016 | L | 28 | 3 | 0 | 4.52 | .304 | .350 | 1.37 | 8.1 | 4.3 | 9.9 | 67 | 60 | 11 | 32 | 74 | 0 | 0 | 6 | 23 | -0.12 | C |
| RP | Jeffress, J.Jeffress, Jeremy >> | 28 | 2016 | R | 36 | 3 | 2 | 2.33 | .284 | .330 | 1.26 | 8.5 | 2.8 | 6.5 | 58 | 55 | 2 | 18 | 42 | 0 | 27 | 3 | 23 | +1.79 | C |
| RP | McAllister, Z.McAllister, Zach >> | 28 | 2016 | R | 18 | 3 | 2 | 3.44 | .314 | .360 | 1.46 | 9.2 | 4.0 | 9.3 | 52 | 53 | 6 | 23 | 54 | 0 | 0 | 3 | 23 | +0.96 | C |
| RP | Young, C.Young, Chris >> | 37 | 2016 | R | 7 | 3 | 9 | 6.19 | .349 | .390 | 1.67 | 10.6 | 4.4 | 9.6 | 88 | 104 | 28 | 43 | 94 | 0 | 1 | 3 | 48 | -1.01 | C |
| RP | Bailey, A.Bailey, Andrew >> | 32 | 2016 | R | 27 | 3 | 1 | 5.36 | .294 | .340 | 1.35 | 8.6 | 3.6 | 8.6 | 43 | 41 | 7 | 17 | 41 | 0 | 6 | 3 | 23 | -0.21 | C |
| RP | Benoit, J.Benoit, Joaquin >> | 39 | 2016 | R | 48 | 3 | 1 | 2.81 | .284 | .330 | 1.27 | 6.9 | 4.5 | 9.8 | 48 | 37 | 5 | 24 | 52 | 0 | 1 | 1 | 23 | +1.06 | C |
| RP | Ogando, A.Ogando, Alexi >> | 32 | 2016 | R | 9 | 2 | 1 | 3.94 | .342 | .400 | 1.72 | 9.0 | 6.5 | 8.2 | 32 | 32 | 2 | 23 | 29 | 0 | 0 | 3 | 23 | -0.03 | C |
| RP | Papelbon, J.Papelbon, Jonathan >> | 36 | 2016 | R | 13 | 2 | 4 | 4.37 | .307 | .360 | 1.46 | 9.5 | 3.6 | 8.0 | 35 | 37 | 3 | 14 | 31 | 0 | 19 | 1 | 23 | +0.02 | C |
| RP | McGee, J.McGee, Jake >> | 29 | 2016 | L | 5 | 2 | 3 | 4.73 | .332 | .380 | 1.60 | 11.2 | 3.2 | 7.6 | 45 | 56 | 9 | 16 | 38 | 0 | 15 | 4 | 23 | +0.32 | C |
| RP | Jepsen, K.Jepsen, Kevin >> | 32 | 2016 | R | 3 | 2 | 6 | 5.98 | .346 | .390 | 1.69 | 11.4 | 3.9 | 6.4 | 49 | 62 | 12 | 21 | 35 | 0 | 7 | 4 | 23 | -0.89 | C |
| RP | Villanueva, C.Villanueva, Carlos >> | 33 | 2016 | R | 11 | 2 | 2 | 5.96 | .307 | .350 | 1.39 | 10.8 | 1.7 | 7.4 | 74 | 89 | 17 | 14 | 61 | 0 | 1 | 2 | 29 | -1.06 | C |
| RP | Wilhelmsen, T.Wilhelmsen, Tom >> | 32 | 2016 | R | 1 | 2 | 4 | 6.80 | .348 | .400 | 1.72 | 11.7 | 3.7 | 5.5 | 46 | 60 | 11 | 19 | 28 | 0 | 1 | 0 | 23 | -0.9 | C |
| RP | Smith, J.Smith, Joe >> | 32 | 2016 | R | 39 | 2 | 5 | 3.46 | .281 | .330 | 1.25 | 8.1 | 3.1 | 6.9 | 52 | 47 | 8 | 18 | 40 | 0 | 6 | 0 | 23 | +0.6 | C |
| RP | Hunter, T.Hunter, Tommy >> | 30 | 2016 | R | 34 | 2 | 2 | 3.18 | .277 | .330 | 1.26 | 9.3 | 2.1 | 6.1 | 34 | 35 | 1 | 8 | 23 | 0 | 0 | 0 | 23 | +0.59 | C |
| RP | Caminero, A.Caminero, Arquimedes >> | 29 | 2016 | R | 6 | 2 | 3 | 3.56 | .345 | .390 | 1.67 | 10.1 | 5.0 | 7.5 | 60 | 67 | 7 | 33 | 50 | 0 | 1 | 2 | 23 | +0.25 | C |
| RP | Tolleson, S.Tolleson, Shawn >> | 28 | 2016 | R | 2 | 2 | 2 | 7.68 | .348 | .400 | 1.75 | 13.3 | 2.5 | 7.3 | 36 | 53 | 8 | 10 | 29 | 0 | 11 | 1 | 23 | -1.3 | C |
| RP | Maness, S.Maness, Seth >> | 27 | 2016 | R | 17 | 2 | 2 | 3.41 | .290 | .340 | 1.35 | 9.9 | 2.3 | 4.6 | 31 | 34 | 2 | 8 | 16 | 0 | 0 | 2 | 23 | +0.27 | C |
| RP | Rosenthal, T.Rosenthal, Trevor >> | 26 | 2016 | R | 8 | 2 | 4 | 4.46 | .372 | .420 | 1.93 | 10.8 | 6.5 | 12.6 | 40 | 48 | 3 | 29 | 56 | 0 | 14 | 0 | 23 | -0.05 | C |
| RP | Rodney, F.Rodney, Fernando >> | 39 | 2016 | R | 34 | 2 | 4 | 3.44 | .307 | .350 | 1.40 | 7.5 | 5.1 | 10.2 | 65 | 54 | 5 | 37 | 74 | 0 | 25 | 5 | 23 | +0.89 | C |
| RP | Henderson, J.Henderson, Jim >> | 33 | 2016 | R | 21 | 2 | 2 | 4.37 | .299 | .350 | 1.40 | 9.0 | 3.6 | 10.3 | 35 | 35 | 7 | 14 | 40 | 0 | 0 | 0 | 23 | +0.12 | C |
| RP | Fien, C.Fien, Casey >> | 32 | 2016 | R | 10 | 1 | 1 | 5.49 | .302 | .350 | 1.41 | 10.4 | 2.3 | 8.1 | 39 | 45 | 13 | 10 | 35 | 0 | 0 | 1 | 23 | -0.35 | C |
| RP | Sipp, T.Sipp, Tony >> | 32 | 2016 | L | 7 | 1 | 2 | 4.95 | .335 | .380 | 1.63 | 10.9 | 3.8 | 8.4 | 43 | 52 | 12 | 18 | 40 | 0 | 1 | 0 | 23 | -0.39 | C |
| RP | Maurer, B.Maurer, Brandon >> | 25 | 2016 | R | 38 | 0 | 5 | 4.52 | .289 | .330 | 1.28 | 8.5 | 3.0 | 9.4 | 69 | 65 | 7 | 23 | 72 | 0 | 13 | 3 | 23 | -0.12 | C |
| RP | Hendriks, L.Hendriks, Liam >> | 27 | 2016 | R | 29 | 0 | 4 | 3.76 | .291 | .330 | 1.30 | 9.7 | 2.0 | 10.0 | 64 | 69 | 6 | 14 | 71 | 0 | 0 | 3 | 25 | +0.73 | C |