| SP | Garland, J.Garland, Jon >> | 27 | 2006 | R | 19 | 18 | 7 | 4.51 | .309 | .350 | 1.36 | 10.5 | 1.7 | 4.8 | 211 | 247 | 26 | 41 | 112 | 1 | 0 | 4 | 107 | +3.67 | C |
| SP | Blanton, J.Blanton, Joe >> | 26 | 2006 | R | 2 | 16 | 12 | 4.82 | .336 | .370 | 1.54 | 11.2 | 2.7 | 5.0 | 194 | 241 | 17 | 58 | 107 | 1 | 0 | 3 | 107 | +1.24 | C |
| SP | Westbrook, J.Westbrook, Jake >> | 29 | 2006 | R | 5 | 15 | 10 | 4.17 | .320 | .360 | 1.43 | 10.5 | 2.3 | 4.6 | 211 | 247 | 15 | 55 | 109 | 3 | 0 | 5 | 105 | +3.55 | C |
| SP | Pettitte, A.Pettitte, Andy >> | 34 | 2006 | L | 13 | 14 | 13 | 4.20 | .321 | .360 | 1.44 | 10.0 | 2.9 | 7.5 | 214 | 238 | 27 | 70 | 178 | 2 | 0 | 2 | 87 | +1.48 | C |
| SP | Buehrle, M.Buehrle, Mark >> | 27 | 2006 | L | 3 | 12 | 13 | 4.99 | .322 | .360 | 1.45 | 10.9 | 2.1 | 4.3 | 204 | 247 | 36 | 48 | 98 | 1 | 0 | 0 | 108 | +2.27 | C |
| SP | Suppan, J.Suppan, Jeff >> | 31 | 2006 | R | 6 | 12 | 7 | 4.12 | .322 | .360 | 1.45 | 9.8 | 3.3 | 4.9 | 190 | 207 | 21 | 69 | 104 | 0 | 0 | 8 | 86 | +1.17 | C |
| SP | Willis, D.Willis, Dontrelle >> | 24 | 2006 | L | 22 | 12 | 12 | 3.87 | .318 | .350 | 1.42 | 9.4 | 3.3 | 6.5 | 223 | 234 | 21 | 83 | 160 | 4 | 0 | 6 | 103 | +4.06 | C |
| SP | Benson, K.Benson, Kris >> | 32 | 2006 | R | 17 | 11 | 12 | 4.82 | .315 | .350 | 1.40 | 9.8 | 2.9 | 4.3 | 183 | 199 | 33 | 58 | 88 | 3 | 0 | 6 | 103 | +1.79 | C |
| SP | Kim, B.Kim, Byung-Hyun >> | 27 | 2006 | R | 7 | 8 | 12 | 5.57 | .336 | .370 | 1.55 | 10.4 | 3.5 | 7.5 | 155 | 179 | 18 | 61 | 129 | 0 | 0 | 5 | 86 | +0.42 | C |
| SP | Shields, J.Shields, James >> | 25 | 2006 | R | 11 | 6 | 8 | 4.84 | .319 | .360 | 1.44 | 10.2 | 2.8 | 7.5 | 124 | 141 | 18 | 38 | 104 | 1 | 0 | 9 | 86 | +1.67 | C |