| RP | Belisle, M.Belisle, Matt >> | 30 | 2010 | R | 45 | 7 | 5 | 2.93 | .259 | .310 | 1.09 | 8.2 | 1.6 | 8.9 | 92 | 84 | 7 | 16 | 91 | 0 | 1 | 3 | 25 | +1.94 | C |
| RP | Coke, P.Coke, Phil >> | 28 | 2010 | L | 2 | 7 | 5 | 3.76 | .315 | .370 | 1.45 | 9.4 | 3.7 | 7.5 | 64 | 67 | 2 | 26 | 53 | 0 | 2 | 3 | 25 | +0.52 | C |
| RP | Contreras, J.Contreras, Jose >> | 39 | 2010 | R | 33 | 6 | 4 | 3.34 | .279 | .330 | 1.23 | 8.5 | 2.6 | 9.2 | 56 | 53 | 5 | 16 | 57 | 0 | 4 | 0 | 25 | +0.9 | C |
| RP | Cordero, F.Cordero, Francisco >> | 35 | 2010 | R | 7 | 6 | 5 | 3.84 | .315 | .370 | 1.44 | 8.5 | 4.5 | 7.4 | 72 | 68 | 5 | 36 | 59 | 0 | 40 | 2 | 25 | +0.29 | C |
| RP | Francisco, F.Francisco, Frank >> | 31 | 2010 | R | 28 | 6 | 4 | 3.76 | .288 | .340 | 1.29 | 8.5 | 3.1 | 10.4 | 52 | 49 | 5 | 18 | 60 | 0 | 2 | 2 | 25 | +0.78 | C |
| RP | Heilman, A.Heilman, Aaron >> | 32 | 2010 | R | 5 | 5 | 8 | 4.50 | .305 | .360 | 1.38 | 9.1 | 3.3 | 6.9 | 72 | 73 | 9 | 26 | 55 | 0 | 6 | 8 | 25 | -0.08 | C |
| RP | Janssen, C.Janssen, Casey >> | 29 | 2010 | R | 3 | 5 | 2 | 3.67 | .307 | .360 | 1.40 | 9.8 | 2.8 | 8.3 | 68 | 74 | 8 | 21 | 63 | 0 | 0 | 3 | 25 | +0.88 | C |
| RP | Broxton, J.Broxton, Jonathan >> | 26 | 2010 | R | 6 | 5 | 6 | 4.04 | .319 | .370 | 1.48 | 9.3 | 4.1 | 10.6 | 62 | 64 | 4 | 28 | 73 | 0 | 22 | 1 | 25 | +0.33 | C |
| RP | Camp, S.Camp, Shawn >> | 35 | 2010 | R | 22 | 4 | 3 | 2.99 | .283 | .330 | 1.24 | 8.9 | 2.3 | 5.8 | 72 | 71 | 8 | 18 | 46 | 0 | 2 | 2 | 25 | +1.63 | C |
| RP | Capuano, C.Capuano, Chris >> | 32 | 2010 | L | 16 | 4 | 4 | 3.95 | .293 | .350 | 1.30 | 8.9 | 2.9 | 7.4 | 66 | 65 | 9 | 21 | 54 | 0 | 0 | 5 | 38 | +0.79 | C |
| RP | Durbin, C.Durbin, Chad >> | 33 | 2010 | R | 19 | 4 | 1 | 3.80 | .296 | .350 | 1.32 | 8.3 | 3.6 | 8.3 | 68 | 63 | 7 | 27 | 63 | 0 | 0 | 0 | 22 | +0.69 | C |
| RP | Masset, N.Masset, Nick >> | 28 | 2010 | R | 36 | 4 | 4 | 3.40 | .290 | .340 | 1.28 | 7.6 | 3.9 | 10.1 | 76 | 64 | 7 | 33 | 85 | 0 | 2 | 8 | 25 | +0.8 | C |
| RP | Nunez, L.Nunez, Leo >> | 27 | 2010 | R | 25 | 4 | 3 | 3.46 | .288 | .340 | 1.28 | 8.6 | 2.9 | 9.8 | 65 | 62 | 5 | 21 | 71 | 0 | 30 | 1 | 25 | +0.99 | C |
| RP | Ogando, A.Ogando, Alexi >> | 26 | 2010 | R | 57 | 4 | 1 | 1.30 | .261 | .320 | 1.15 | 6.8 | 3.5 | 8.6 | 41 | 31 | 2 | 16 | 39 | 0 | 0 | 3 | 25 | +2.04 | C |
| RP | Robertson, D.Robertson, David >> | 25 | 2010 | R | 11 | 4 | 5 | 3.82 | .323 | .380 | 1.51 | 8.7 | 4.9 | 10.5 | 61 | 59 | 5 | 33 | 71 | 0 | 1 | 7 | 25 | +0.78 | C |
| RP | Storen, D.Storen, Drew >> | 22 | 2010 | R | 32 | 4 | 4 | 3.58 | .286 | .340 | 1.27 | 7.9 | 3.6 | 8.5 | 55 | 48 | 3 | 22 | 52 | 0 | 5 | 3 | 22 | +0.41 | C |
| RP | Street, H.Street, Huston >> | 27 | 2010 | R | 61 | 4 | 4 | 3.61 | .249 | .300 | 1.06 | 7.5 | 2.1 | 8.6 | 47 | 39 | 5 | 11 | 45 | 0 | 20 | 2 | 23 | +0.76 | C |
| RP | Linebrink, S.Linebrink, Scott >> | 34 | 2010 | R | 10 | 3 | 2 | 4.40 | .296 | .350 | 1.33 | 9.3 | 2.7 | 8.2 | 57 | 59 | 11 | 17 | 52 | 0 | 0 | 7 | 20 | +0.39 | C |
| RP | Rauch, J.Rauch, Jon >> | 32 | 2010 | R | 8 | 3 | 1 | 3.12 | .293 | .350 | 1.32 | 9.6 | 2.2 | 7.3 | 57 | 61 | 3 | 14 | 46 | 0 | 21 | 1 | 25 | +1.23 | C |
| RP | Frasor, J.Frasor, Jason >> | 33 | 2010 | R | 13 | 3 | 4 | 3.68 | .307 | .360 | 1.40 | 8.7 | 3.9 | 9.3 | 63 | 61 | 4 | 27 | 65 | 0 | 4 | 5 | 25 | +0.65 | C |
| RP | Chamberlain, J.Chamberlain, Joba >> | 25 | 2010 | R | 18 | 3 | 4 | 4.40 | .294 | .350 | 1.31 | 9.0 | 2.8 | 9.8 | 71 | 71 | 6 | 22 | 77 | 0 | 3 | 5 | 25 | +0.05 | C |
| RP | Dotel, O.Dotel, Octavio >> | 37 | 2010 | R | 37 | 3 | 4 | 4.08 | .294 | .350 | 1.31 | 7.3 | 4.5 | 10.5 | 64 | 52 | 9 | 32 | 75 | 0 | 22 | 8 | 25 | +0.43 | C |
| RP | Villanueva, C.Villanueva, Carlos >> | 27 | 2010 | R | 26 | 2 | 0 | 4.61 | .297 | .350 | 1.35 | 8.3 | 3.8 | 11.6 | 52 | 48 | 7 | 22 | 67 | 0 | 1 | 5 | 25 | -0.11 | C |
| RP | Oliver, D.Oliver, Darren >> | 40 | 2010 | L | 47 | 1 | 2 | 2.48 | .261 | .310 | 1.11 | 7.8 | 2.2 | 9.6 | 61 | 53 | 4 | 15 | 65 | 0 | 1 | 0 | 25 | +1.68 | C |
| RP | Jenks, B.Jenks, Bobby >> | 29 | 2010 | R | 12 | 1 | 3 | 4.44 | .303 | .360 | 1.38 | 9.3 | 3.1 | 10.6 | 52 | 54 | 3 | 18 | 61 | 0 | 27 | 2 | 25 | +0.26 | C |
| RP | Lidge, B.Lidge, Brad >> | 34 | 2010 | R | 49 | 1 | 1 | 2.96 | .279 | .340 | 1.24 | 6.4 | 4.8 | 10.4 | 45 | 32 | 5 | 24 | 52 | 0 | 27 | 3 | 25 | +1.06 | C |
| RP | Aardsma, D.Aardsma, David >> | 29 | 2010 | R | 63 | 0 | 6 | 3.44 | .270 | .330 | 1.18 | 6.1 | 4.6 | 9.0 | 49 | 33 | 5 | 25 | 49 | 0 | 31 | 2 | 25 | +0.68 | C |