| SP | Rogers, K.Rogers, Kenny >> | 44 | 2006 | L | 29 | 17 | 8 | 3.84 | .301 | .350 | 1.31 | 8.8 | 3.0 | 4.1 | 204 | 200 | 23 | 68 | 94 | 0 | 0 | 5 | 103 | 12 | C |
| SP | Ponson, S.Ponson, Sidney >> | 32 | 2003 | R | 52 | 17 | 12 | 3.75 | .280 | .330 | 1.18 | 8.6 | 2.1 | 5.8 | 222 | 211 | 16 | 52 | 144 | 4 | 0 | 9 | 130 | 20 | C |
| SP | Hernandez, O.Hernandez, Orlando >> | 43 | 2004 | R | 34 | 16 | 4 | 3.30 | .313 | .360 | 1.39 | 8.3 | 4.3 | 8.6 | 168 | 154 | 18 | 80 | 160 | 0 | 0 | 6 | 95 | 15 | C |
| SP | Maddux, G.Maddux, Greg >> | 42 | 2003 | R | 26 | 16 | 11 | 3.96 | .295 | .340 | 1.28 | 9.7 | 1.8 | 4.5 | 218 | 234 | 24 | 44 | 109 | 1 | 0 | 3 | 97 | 10 | C |
| SP | Moyer, J.Moyer, Jamie >> | 46 | 2008 | L | 24 | 16 | 7 | 3.71 | .304 | .350 | 1.33 | 9.1 | 2.8 | 5.6 | 196 | 199 | 20 | 62 | 123 | 0 | 0 | 3 | 105 | 15 | C |
| SP | Marquis, J.Marquis, Jason >> | 30 | 2004 | R | 27 | 15 | 7 | 3.71 | .302 | .350 | 1.32 | 9.2 | 2.6 | 6.4 | 211 | 216 | 26 | 62 | 149 | 0 | 0 | 6 | 116 | 19 | C |
| SP | Alvarez, W.Alvarez, Wilson >> | 38 | 2003 | L | 62 | 12 | 4 | 2.37 | .284 | .330 | 1.21 | 8.1 | 2.7 | 7.1 | 190 | 172 | 10 | 58 | 150 | 1 | 2 | 2 | 74 | 13 | C |
| SP | Davis, D.Davis, Doug >> | 33 | 2004 | L | 36 | 12 | 12 | 3.39 | .302 | .350 | 1.32 | 8.4 | 3.4 | 7.2 | 209 | 196 | 14 | 79 | 167 | 0 | 0 | 4 | 110 | 18 | C |
| SP | Moehler, B.Moehler, Brian >> | 37 | 2008 | R | 17 | 11 | 8 | 4.56 | .305 | .350 | 1.35 | 10.0 | 2.2 | 4.9 | 150 | 166 | 20 | 36 | 82 | 0 | 0 | 3 | 86 | 15 | C |
| SP | Radke, B.Radke, Brad >> | 36 | 2004 | R | 29 | 11 | 8 | 3.48 | .289 | .340 | 1.24 | 9.8 | 1.4 | 5.4 | 219 | 238 | 23 | 33 | 131 | 1 | 0 | 2 | 107 | 11 | C |
| SP | Blackburn, N.Blackburn, Nick >> | 26 | 2008 | R | 13 | 11 | 11 | 4.05 | .309 | .360 | 1.36 | 10.4 | 1.8 | 4.5 | 193 | 224 | 23 | 39 | 96 | 0 | 0 | 2 | 103 | 14 | C |
| SP | Byrd, P.Byrd, Paul >> | 38 | 2008 | R | 18 | 11 | 12 | 4.60 | .302 | .350 | 1.32 | 10.2 | 1.7 | 4.1 | 180 | 204 | 31 | 34 | 82 | 1 | 0 | 0 | 106 | 14 | C |
| SP | Suppan, J.Suppan, Jeff >> | 33 | 2008 | R | 3 | 10 | 10 | 4.96 | .336 | .390 | 1.55 | 10.5 | 3.4 | 4.6 | 177 | 207 | 30 | 67 | 90 | 0 | 0 | 3 | 101 | 14 | C |
| SP | Washburn, J.Washburn, Jarrod >> | 34 | 2007 | L | 16 | 10 | 15 | 4.32 | .317 | .370 | 1.42 | 9.5 | 3.3 | 5.3 | 193 | 203 | 23 | 71 | 113 | 1 | 0 | 2 | 106 | 14 | C |
| SP | Eveland, D.Eveland, Dana >> | 25 | 2008 | L | 18 | 9 | 9 | 4.34 | .326 | .380 | 1.48 | 9.2 | 4.1 | 6.3 | 168 | 172 | 10 | 77 | 118 | 1 | 0 | 6 | 102 | 16 | C |
| SP | Hendrickson, M.Hendrickson, Mark >> | 34 | 2008 | L | 11 | 7 | 8 | 5.45 | .324 | .370 | 1.47 | 10.0 | 3.2 | 5.5 | 133 | 148 | 17 | 48 | 81 | 0 | 0 | 4 | 67 | 15 | C |
| SP | Smith, G.Smith, Greg >> | 25 | 2008 | L | 31 | 7 | 16 | 4.16 | .306 | .350 | 1.35 | 8.0 | 4.1 | 5.3 | 190 | 169 | 21 | 87 | 111 | 2 | 0 | 5 | 105 | 15 | C |
| SP | Gonzalez, G.Gonzalez, Geremi >> | 33 | 2003 | R | 45 | 6 | 11 | 3.91 | .297 | .350 | 1.30 | 7.8 | 3.9 | 5.3 | 159 | 137 | 18 | 69 | 93 | 2 | 0 | 3 | 112 | 14 | C |
| SP | Rusch, G.Rusch, Glendon >> | 34 | 2004 | L | 26 | 6 | 2 | 3.47 | .301 | .350 | 1.33 | 9.2 | 2.7 | 6.0 | 129 | 132 | 10 | 39 | 86 | 0 | 2 | 1 | 70 | 14 | C |
| SP | Rasner, D.Rasner, Darrell >> | 27 | 2008 | R | 5 | 5 | 10 | 5.40 | .333 | .380 | 1.54 | 10.8 | 3.1 | 5.3 | 113 | 135 | 14 | 39 | 67 | 0 | 0 | 4 | 84 | 15 | C |
| SP | Gallagher, S.Gallagher, Sean >> | 23 | 2008 | R | 20 | 5 | 7 | 5.15 | .331 | .380 | 1.53 | 9.2 | 4.5 | 8.1 | 115 | 118 | 13 | 58 | 103 | 0 | 0 | 2 | 89 | 18 | C |
| SP | Braden, D.Braden, Dallas >> | 25 | 2008 | L | 13 | 5 | 4 | 4.14 | .314 | .370 | 1.44 | 9.8 | 3.2 | 5.2 | 71 | 77 | 8 | 25 | 41 | 0 | 0 | 0 | 68 | 15 | C |
| SP | Vargas, J.Vargas, Jason >> | 25 | 2005 | L | 19 | 5 | 5 | 4.03 | .322 | .380 | 1.49 | 9.4 | 4.0 | 7.4 | 74 | 77 | 4 | 33 | 61 | 1 | 0 | 0 | 79 | 17 | C |
| SP | Colon, B.Colon, Bartolo >> | 35 | 2008 | R | 16 | 4 | 2 | 3.92 | .298 | .360 | 1.38 | 10.2 | 2.3 | 6.2 | 39 | 44 | 5 | 10 | 27 | 0 | 0 | 0 | 99 | 16 | C |
| SP | Baek, C.Baek, Cha Seung >> | 28 | 2007 | R | 22 | 4 | 3 | 5.15 | .298 | .350 | 1.33 | 10.3 | 1.7 | 6.5 | 76 | 87 | 6 | 14 | 55 | 1 | 0 | 1 | 95 | 17 | C |
| SP | Morton, C.Morton, Charlie >> | 25 | 2008 | R | 8 | 4 | 8 | 6.15 | .343 | .400 | 1.64 | 9.7 | 5.0 | 5.8 | 74 | 80 | 9 | 41 | 48 | 0 | 0 | 2 | 83 | 16 | C |
| SP | Eaton, A.Eaton, Adam >> | 31 | 2008 | R | 2 | 4 | 8 | 5.80 | .346 | .400 | 1.64 | 11.0 | 3.7 | 4.8 | 107 | 131 | 15 | 44 | 57 | 0 | 0 | 2 | 91 | 15 | C |
| SP | Purcey, D.Purcey, David >> | 26 | 2008 | L | 21 | 3 | 6 | 5.54 | .319 | .370 | 1.48 | 9.3 | 4.0 | 8.0 | 65 | 67 | 9 | 29 | 58 | 1 | 0 | 3 | 96 | 18 | C |
| SP | Reyes, J.Reyes, Jo-Jo >> | 24 | 2008 | L | 4 | 3 | 11 | 5.81 | .348 | .400 | 1.65 | 10.7 | 4.1 | 6.2 | 113 | 134 | 18 | 52 | 78 | 0 | 0 | 2 | 88 | 16 | C |
| SP | Hampton, M.Hampton, Mike >> | 36 | 2008 | L | 14 | 3 | 4 | 4.85 | .313 | .370 | 1.42 | 9.6 | 3.2 | 4.4 | 78 | 83 | 10 | 28 | 38 | 0 | 0 | 0 | 106 | 14 | C |
| SP | Glavine, T.Glavine, Tom >> | 42 | 2008 | L | 6 | 2 | 4 | 5.54 | .343 | .400 | 1.65 | 9.6 | 5.3 | 5.3 | 63 | 67 | 11 | 37 | 37 | 0 | 0 | 0 | 86 | 15 | C |
| SP | Jackson, Z.Jackson, Zach >> | 25 | 2008 | L | 8 | 2 | 3 | 5.55 | .316 | .370 | 1.47 | 10.7 | 2.5 | 4.8 | 58 | 69 | 7 | 16 | 31 | 0 | 0 | 2 | 94 | 15 | C |
| SP | Badenhop, B.Badenhop, Burke >> | 25 | 2008 | R | 9 | 2 | 3 | 6.08 | .335 | .400 | 1.62 | 10.5 | 4.0 | 6.7 | 47 | 55 | 7 | 21 | 35 | 0 | 0 | 2 | 65 | 17 | C |
| SP | Feierabend, R.Feierabend, Ryan >> | 23 | 2008 | L | 1 | 1 | 4 | 7.71 | .365 | .430 | 1.87 | 13.6 | 3.2 | 6.0 | 39 | 59 | 7 | 14 | 26 | 0 | 0 | 1 | 87 | 16 | C |
| SP | Misch, P.Misch, Patrick >> | 27 | 2008 | L | 21 | 0 | 3 | 5.68 | .300 | .360 | 1.37 | 9.7 | 2.6 | 6.6 | 52 | 56 | 11 | 15 | 38 | 0 | 0 | 1 | 63 | 17 | C |