| SP | Bahnsen, S.Bahnsen, Stan >> | 30 | 1974 | R | 13 | 12 | 15 | 4.70 | .341 | .400 | 1.57 | 9.6 | 4.6 | 4.3 | 216 | 230 | 17 | 110 | 102 | 10 | 0 | 8 | 101 | 0 | C |
| SP | Noesi, H.Noesi, Hector >> | 27 | 2014 | R | 27 | 8 | 11 | 4.39 | .303 | .360 | 1.33 | 9.1 | 2.9 | 6.3 | 166 | 167 | 27 | 54 | 117 | 1 | 0 | 8 | 105 | -0.25 | C |
| SP | Martinez, D.Martinez, Dennis >> | 28 | 1983 | R | 3 | 7 | 16 | 5.53 | .351 | .410 | 1.66 | 12.3 | 2.6 | 4.2 | 153 | 209 | 21 | 45 | 71 | 4 | 0 | 2 | 85 | -1.78 | C |
| SP | Wacha, M.Wacha, Michael >> | 27 | 2019 | R | 14 | 6 | 7 | 4.76 | .338 | .400 | 1.57 | 10.2 | 3.9 | 7.4 | 126 | 143 | 26 | 55 | 104 | 0 | 0 | 2 | 78 | +0.24 | C |
| SP | Watson, A.Watson, Allen >> | 24 | 1994 | L | 10 | 6 | 5 | 5.52 | .340 | .400 | 1.59 | 10.2 | 4.1 | 5.8 | 115 | 130 | 15 | 53 | 74 | 0 | 0 | 2 | 93 | -0.73 | C |
| SP | Villone, R.Villone, Ron >> | 33 | 2003 | L | 42 | 6 | 6 | 4.13 | .298 | .360 | 1.31 | 7.7 | 4.1 | 7.7 | 106 | 91 | 16 | 48 | 91 | 0 | 0 | 1 | 99 | +0.92 | C |
| SP | Bennett, D.Bennett, Dennis >> | 26 | 1965 | L | 19 | 5 | 7 | 4.38 | .321 | .380 | 1.45 | 9.7 | 3.4 | 5.4 | 141 | 152 | 15 | 53 | 85 | 3 | 0 | 4 | 74 | +0.57 | C |
| SP | Liriano, F.Liriano, Francisco >> | 26 | 2009 | L | 16 | 5 | 13 | 5.80 | .337 | .400 | 1.56 | 9.7 | 4.3 | 8.1 | 136 | 147 | 21 | 65 | 122 | 0 | 0 | 5 | 84 | -0.2 | C |
| SP | Thomas, T.Thomas, Tommy >> | 31 | 1930 | R | 2 | 5 | 13 | 5.22 | .346 | .410 | 1.62 | 12.2 | 2.3 | 3.1 | 169 | 229 | 13 | 44 | 58 | 7 | 0 | 0 | 88 | +0.05 | C |
| SP | Heaney, A.Heaney, Andrew >> | 34 | 2025 | L | 21 | 5 | 10 | 5.52 | .310 | .370 | 1.39 | 9.5 | 3.0 | 6.3 | 122 | 129 | 25 | 40 | 86 | 0 | 0 | 2 | 81 | -0.4 | C |
| SP | O'Toole, J.O'Toole, Jim >> | 28 | 1965 | L | 5 | 3 | 10 | 5.92 | .340 | .400 | 1.58 | 10.9 | 3.3 | 5.0 | 127 | 154 | 14 | 47 | 71 | 2 | 1 | 4 | 78 | 0 | C |
| SP | Stratton, S.Stratton, Scott >> | 20 | 1889 | R | 8 | 3 | 13 | 3.23 | .327 | .390 | 1.50 | 10.6 | 2.8 | 2.8 | 133 | 157 | 6 | 42 | 42 | 13 | 1 | 3 | 123 | -1.06 | C |