| SP | Flexen, C.Flexen, Christopher >> | 26 | 2021 | R | 28 | 14 | 6 | 3.61 | .291 | .340 | 1.26 | 9.3 | 2.0 | 6.3 | 179 | 185 | 19 | 40 | 125 | 0 | 0 | 2 | 102 | 16 | C |
| SP | Hendricks, K.Hendricks, Kyle >> | 31 | 2021 | R | 15 | 14 | 7 | 4.77 | .306 | .350 | 1.35 | 9.9 | 2.2 | 6.5 | 181 | 200 | 31 | 44 | 131 | 1 | 0 | 2 | 100 | 16 | C |
| SP | Matz, S.Matz, Steven >> | 30 | 2021 | L | 21 | 14 | 7 | 3.82 | .304 | .350 | 1.34 | 9.5 | 2.6 | 8.6 | 150 | 158 | 18 | 43 | 144 | 0 | 0 | 5 | 92 | 19 | C |
| SP | Ryu, H.Ryu, Hyun-jin >> | 34 | 2021 | L | 41 | 14 | 10 | 4.37 | .286 | .330 | 1.22 | 9.1 | 2.0 | 7.6 | 169 | 170 | 24 | 37 | 143 | 1 | 0 | 2 | 97 | 17 | C |
| SP | Rodriguez, E.Rodriguez, Eduardo >> | 28 | 2021 | L | 20 | 13 | 8 | 4.74 | .313 | .360 | 1.39 | 9.9 | 2.7 | 10.6 | 157 | 172 | 19 | 47 | 185 | 0 | 0 | 0 | 87 | 20 | C |
| SP | Miley, W.Miley, Wade >> | 34 | 2021 | L | 22 | 12 | 7 | 3.37 | .302 | .350 | 1.33 | 9.2 | 2.8 | 6.9 | 163 | 166 | 17 | 50 | 125 | 1 | 0 | 2 | 103 | 16 | C |
| SP | Marquez, G.Marquez, German >> | 26 | 2021 | R | 43 | 12 | 11 | 4.40 | .294 | .340 | 1.27 | 8.3 | 3.2 | 8.8 | 180 | 165 | 21 | 64 | 176 | 3 | 0 | 15 | 100 | 18 | C |
| SP | Manaea, S.Manaea, Sean >> | 29 | 2021 | L | 47 | 11 | 10 | 3.91 | .287 | .330 | 1.23 | 9.0 | 2.1 | 9.8 | 179 | 179 | 25 | 41 | 194 | 2 | 0 | 5 | 99 | 20 | C |
| SP | Smyly, D.Smyly, Drew >> | 32 | 2021 | L | 19 | 11 | 4 | 4.48 | .310 | .360 | 1.38 | 9.5 | 2.9 | 8.4 | 126 | 133 | 27 | 41 | 117 | 0 | 0 | 5 | 78 | 18 | C |
| SP | Eovaldi, N.Eovaldi, Nathan >> | 31 | 2021 | R | 50 | 11 | 9 | 3.75 | .281 | .330 | 1.19 | 9.0 | 1.7 | 9.6 | 182 | 182 | 15 | 35 | 195 | 0 | 0 | 6 | 101 | 19 | C |
| SP | Houser, A.Houser, Adrian >> | 28 | 2021 | R | 46 | 10 | 6 | 3.22 | .294 | .340 | 1.28 | 7.5 | 4.1 | 6.7 | 142 | 118 | 12 | 64 | 105 | 1 | 0 | 9 | 90 | 17 | C |
| SP | Irvin, C.Irvin, Cole >> | 27 | 2021 | L | 19 | 10 | 15 | 4.24 | .303 | .350 | 1.33 | 9.9 | 2.1 | 6.3 | 178 | 195 | 23 | 42 | 125 | 0 | 0 | 3 | 99 | 16 | C |
| SP | Happ, J.Happ, J.A. >> | 39 | 2021 | L | 7 | 10 | 8 | 5.79 | .326 | .370 | 1.48 | 10.5 | 2.8 | 7.2 | 152 | 177 | 30 | 48 | 122 | 0 | 0 | 4 | 90 | 17 | C |
| SP | Lyles, J.Lyles, Jordan >> | 30 | 2021 | R | 14 | 10 | 13 | 5.15 | .313 | .360 | 1.39 | 9.7 | 2.8 | 7.3 | 180 | 194 | 38 | 56 | 146 | 0 | 0 | 9 | 100 | 17 | C |
| SP | McClanahan, S.McClanahan, Shane >> | 24 | 2021 | L | 40 | 10 | 6 | 3.43 | .293 | .340 | 1.28 | 8.8 | 2.7 | 10.3 | 123 | 120 | 14 | 37 | 141 | 0 | 0 | 9 | 88 | 20 | C |
| SP | Plesac, Z.Plesac, Zach >> | 26 | 2021 | R | 48 | 10 | 6 | 4.67 | .282 | .330 | 1.20 | 8.7 | 2.2 | 6.3 | 142 | 137 | 23 | 34 | 100 | 0 | 0 | 5 | 101 | 16 | C |
| SP | Pineda, M.Pineda, Michael >> | 32 | 2021 | R | 35 | 9 | 8 | 3.62 | .286 | .340 | 1.24 | 9.4 | 1.7 | 7.3 | 109 | 114 | 17 | 21 | 88 | 0 | 0 | 1 | 88 | 17 | C |
| SP | Pivetta, N.Pivetta, Nick >> | 28 | 2021 | R | 43 | 9 | 8 | 4.53 | .298 | .350 | 1.30 | 8.0 | 3.8 | 10.2 | 155 | 137 | 24 | 65 | 175 | 0 | 1 | 9 | 89 | 20 | C |
| SP | Yarbrough, R.Yarbrough, Ryan >> | 29 | 2021 | L | 37 | 9 | 7 | 5.11 | .286 | .330 | 1.23 | 9.5 | 1.6 | 6.8 | 155 | 163 | 25 | 27 | 117 | 1 | 0 | 1 | 92 | 16 | C |
| SP | Keuchel, D.Keuchel, Dallas >> | 33 | 2021 | L | 4 | 9 | 9 | 5.28 | .333 | .380 | 1.53 | 10.5 | 3.3 | 5.3 | 162 | 189 | 25 | 59 | 95 | 0 | 0 | 5 | 90 | 15 | C |
| SP | Gomber, A.Gomber, Austin >> | 27 | 2021 | L | 49 | 9 | 9 | 4.53 | .287 | .340 | 1.24 | 8.0 | 3.2 | 8.8 | 115 | 102 | 20 | 41 | 113 | 0 | 0 | 1 | 89 | 19 | C |
| SP | Corbin, P.Corbin, Patrick >> | 31 | 2021 | L | 10 | 9 | 16 | 5.82 | .325 | .370 | 1.47 | 10.1 | 3.2 | 7.5 | 171 | 192 | 37 | 60 | 143 | 0 | 0 | 0 | 98 | 17 | C |
| SP | Castillo, L.Castillo, Luis >> | 28 | 2021 | R | 26 | 8 | 16 | 3.98 | .310 | .360 | 1.37 | 8.7 | 3.6 | 9.2 | 187 | 181 | 19 | 75 | 192 | 0 | 0 | 1 | 100 | 19 | C |
| SP | Cobb, A.Cobb, Alex >> | 33 | 2021 | R | 46 | 8 | 3 | 3.76 | .290 | .340 | 1.27 | 8.2 | 3.2 | 9.5 | 93 | 85 | 5 | 33 | 98 | 0 | 0 | 4 | 92 | 19 | C |
| SP | Gray, J.Gray, Jon >> | 29 | 2021 | R | 34 | 8 | 12 | 4.59 | .302 | .350 | 1.33 | 8.5 | 3.5 | 9.5 | 149 | 140 | 21 | 58 | 157 | 0 | 0 | 7 | 91 | 19 | C |
| SP | Keller, B.Keller, Brad >> | 25 | 2021 | R | 4 | 8 | 12 | 5.39 | .352 | .400 | 1.67 | 10.7 | 4.3 | 8.1 | 133 | 158 | 18 | 64 | 120 | 0 | 0 | 5 | 91 | 18 | C |
| SP | Heaney, A.Heaney, Andrew >> | 30 | 2021 | L | 30 | 8 | 9 | 5.83 | .301 | .350 | 1.33 | 9.1 | 2.9 | 10.5 | 129 | 130 | 29 | 41 | 150 | 0 | 0 | 4 | 77 | 20 | C |
| SP | Skubal, T.Skubal, Tarik >> | 24 | 2021 | L | 44 | 8 | 12 | 4.34 | .291 | .340 | 1.26 | 8.5 | 2.8 | 9.9 | 149 | 141 | 35 | 47 | 164 | 0 | 0 | 4 | 86 | 20 | C |
| SP | Suarez, J.Suarez, Jose >> | 23 | 2021 | L | 51 | 8 | 8 | 3.75 | .285 | .340 | 1.23 | 7.8 | 3.3 | 7.8 | 98 | 85 | 11 | 36 | 85 | 1 | 0 | 4 | 76 | 18 | C |
| SP | Minor, M.Minor, Mike >> | 33 | 2021 | L | 42 | 8 | 12 | 5.05 | .289 | .340 | 1.25 | 8.9 | 2.3 | 8.5 | 158 | 156 | 26 | 41 | 149 | 0 | 0 | 4 | 100 | 18 | C |
| SP | Paddack, C.Paddack, Chris >> | 25 | 2021 | R | 28 | 7 | 7 | 5.07 | .291 | .340 | 1.27 | 9.6 | 1.8 | 8.3 | 108 | 115 | 15 | 22 | 99 | 0 | 0 | 2 | 84 | 18 | C |
| SP | Richards, G.Richards, Garrett >> | 33 | 2021 | R | 6 | 7 | 8 | 4.87 | .343 | .390 | 1.60 | 10.5 | 4.0 | 7.6 | 136 | 158 | 19 | 60 | 115 | 0 | 3 | 7 | 62 | 17 | C |
| SP | Kikuchi, Y.Kikuchi, Yusei >> | 30 | 2021 | L | 37 | 7 | 9 | 4.41 | .301 | .350 | 1.32 | 8.3 | 3.6 | 9.3 | 157 | 145 | 27 | 62 | 163 | 0 | 0 | 6 | 96 | 19 | C |
| SP | Hyun Kim, K.Hyun Kim, Kwang >> | 32 | 2021 | L | 31 | 7 | 7 | 3.46 | .295 | .340 | 1.29 | 8.3 | 3.3 | 6.8 | 106 | 98 | 12 | 39 | 80 | 0 | 1 | 4 | 71 | 17 | C |
| SP | Lester, J.Lester, Jon >> | 37 | 2021 | L | 7 | 7 | 6 | 4.71 | .331 | .380 | 1.52 | 10.1 | 3.5 | 5.8 | 141 | 159 | 25 | 55 | 91 | 0 | 0 | 0 | 90 | 16 | C |
| SP | Kelly, M.Kelly, Merrill >> | 32 | 2021 | R | 27 | 7 | 11 | 4.44 | .297 | .340 | 1.29 | 9.3 | 2.3 | 7.4 | 158 | 163 | 21 | 41 | 130 | 0 | 0 | 2 | 103 | 17 | C |
| SP | Freeland, K.Freeland, Kyle >> | 28 | 2021 | L | 13 | 7 | 8 | 4.33 | .316 | .370 | 1.43 | 10.0 | 2.9 | 7.9 | 120 | 133 | 20 | 38 | 105 | 0 | 0 | 1 | 93 | 18 | C |
| SP | Anderson, T.Anderson, Tyler >> | 31 | 2021 | L | 34 | 7 | 11 | 4.53 | .289 | .340 | 1.25 | 9.2 | 2.0 | 7.2 | 167 | 170 | 27 | 38 | 134 | 0 | 0 | 1 | 96 | 17 | C |
| SP | Cueto, J.Cueto, Johnny >> | 35 | 2021 | R | 16 | 7 | 7 | 4.08 | .308 | .360 | 1.38 | 10.0 | 2.4 | 7.7 | 114 | 127 | 15 | 30 | 98 | 0 | 0 | 0 | 92 | 18 | C |
| SP | Fedde, E.Fedde, Erick >> | 28 | 2021 | R | 16 | 7 | 9 | 5.47 | .319 | .370 | 1.44 | 9.7 | 3.2 | 8.7 | 133 | 144 | 23 | 48 | 128 | 0 | 0 | 1 | 82 | 19 | C |
| SP | Davies, Z.Davies, Zach >> | 28 | 2021 | R | 8 | 6 | 12 | 5.78 | .343 | .390 | 1.60 | 9.9 | 4.6 | 6.9 | 148 | 162 | 25 | 75 | 114 | 0 | 0 | 0 | 83 | 17 | C |
| SP | Bubic, K.Bubic, Kris >> | 23 | 2021 | L | 25 | 6 | 7 | 4.43 | .310 | .360 | 1.38 | 8.4 | 4.1 | 7.9 | 130 | 121 | 22 | 59 | 114 | 0 | 0 | 0 | 80 | 18 | C |
| SP | Luzardo, J.Luzardo, Jesus >> | 23 | 2021 | L | 10 | 6 | 9 | 6.61 | .343 | .390 | 1.62 | 10.0 | 4.5 | 9.3 | 95 | 106 | 20 | 48 | 98 | 0 | 0 | 8 | 69 | 19 | C |
| SP | Harvey, M.Harvey, Matt >> | 32 | 2021 | R | 3 | 6 | 14 | 6.27 | .335 | .380 | 1.55 | 11.3 | 2.6 | 6.7 | 127 | 160 | 19 | 37 | 95 | 0 | 0 | 3 | 81 | 16 | C |
| SP | Odorizzi, J.Odorizzi, Jake >> | 31 | 2021 | R | 40 | 6 | 7 | 4.21 | .289 | .340 | 1.26 | 8.4 | 2.9 | 7.9 | 104 | 97 | 16 | 34 | 91 | 0 | 0 | 0 | 78 | 18 | C |
| SP | Montgomery, J.Montgomery, Jordan >> | 28 | 2021 | L | 39 | 6 | 7 | 3.83 | .295 | .340 | 1.28 | 8.6 | 2.9 | 9.3 | 157 | 150 | 19 | 51 | 162 | 0 | 0 | 12 | 93 | 19 | C |
| SP | Mills, A.Mills, Alec >> | 29 | 2021 | R | 9 | 6 | 7 | 5.07 | .318 | .370 | 1.44 | 10.4 | 2.6 | 6.6 | 119 | 137 | 16 | 34 | 87 | 0 | 1 | 4 | 67 | 16 | C |
| SP | Maeda, K.Maeda, Kenta >> | 33 | 2021 | R | 32 | 6 | 5 | 4.66 | .296 | .350 | 1.30 | 9.0 | 2.7 | 9.6 | 106 | 106 | 16 | 32 | 113 | 0 | 0 | 3 | 90 | 20 | C |
| SP | Singer, B.Singer, Brady >> | 24 | 2021 | R | 11 | 5 | 10 | 4.91 | .336 | .390 | 1.55 | 10.3 | 3.7 | 9.2 | 128 | 146 | 14 | 53 | 131 | 1 | 0 | 3 | 85 | 19 | C |
| SP | Stripling, R.Stripling, Ross >> | 31 | 2021 | R | 36 | 5 | 7 | 4.80 | .292 | .340 | 1.28 | 8.8 | 2.7 | 8.4 | 101 | 99 | 23 | 30 | 94 | 0 | 0 | 0 | 76 | 18 | C |
| SP | Arrieta, J.Arrieta, Jake >> | 35 | 2021 | R | 2 | 5 | 14 | 7.39 | .365 | .420 | 1.79 | 12.0 | 4.0 | 7.6 | 98 | 131 | 24 | 44 | 83 | 0 | 0 | 3 | 73 | 18 | C |
| SP | Brubaker, J.Brubaker, JT >> | 27 | 2021 | R | 33 | 5 | 13 | 5.36 | .297 | .350 | 1.30 | 8.9 | 2.8 | 9.4 | 124 | 123 | 28 | 38 | 129 | 0 | 0 | 3 | 92 | 19 | C |
| SP | Dunning, D.Dunning, Dane >> | 26 | 2021 | R | 17 | 5 | 10 | 4.51 | .319 | .370 | 1.44 | 9.7 | 3.3 | 8.8 | 117 | 126 | 13 | 43 | 114 | 0 | 0 | 8 | 78 | 18 | C |
| SP | Eflin, Z.Eflin, Zach >> | 27 | 2021 | R | 29 | 4 | 7 | 4.17 | .289 | .340 | 1.26 | 9.9 | 1.4 | 8.5 | 105 | 116 | 15 | 16 | 99 | 0 | 0 | 2 | 103 | 19 | C |
| SP | Anderson, B.Anderson, Brett >> | 33 | 2021 | L | 18 | 4 | 9 | 4.22 | .304 | .350 | 1.35 | 9.6 | 2.6 | 5.4 | 96 | 102 | 11 | 28 | 58 | 0 | 0 | 0 | 72 | 15 | C |
| SP | Gallen, Z.Gallen, Zac >> | 25 | 2021 | R | 45 | 4 | 10 | 4.30 | .296 | .350 | 1.30 | 8.0 | 3.6 | 10.3 | 121 | 108 | 19 | 49 | 139 | 1 | 0 | 6 | 93 | 20 | C |
| SP | Williams, T.Williams, Trevor >> | 29 | 2021 | R | 12 | 4 | 2 | 4.35 | .325 | .380 | 1.49 | 10.4 | 3.1 | 8.9 | 91 | 105 | 11 | 31 | 90 | 0 | 0 | 0 | 71 | 19 | C |
| SP | Senzatela, A.Senzatela, Antonio >> | 26 | 2021 | R | 13 | 4 | 10 | 4.42 | .305 | .350 | 1.35 | 10.3 | 1.8 | 6.1 | 156 | 178 | 12 | 32 | 105 | 0 | 0 | 4 | 99 | 16 | C |
| SP | Urena, J.Urena, Jose >> | 29 | 2021 | R | 1 | 4 | 8 | 5.81 | .342 | .390 | 1.61 | 10.7 | 3.8 | 6.0 | 100 | 119 | 14 | 42 | 67 | 0 | 0 | 4 | 69 | 16 | C |
| SP | Megill, T.Megill, Tylor >> | 25 | 2021 | R | 38 | 4 | 6 | 4.52 | .293 | .340 | 1.29 | 8.9 | 2.7 | 10.0 | 89 | 88 | 19 | 27 | 99 | 1 | 0 | 1 | 88 | 21 | C |
| SP | Ober, B.Ober, Bailey >> | 25 | 2021 | R | 49 | 3 | 3 | 4.19 | .280 | .330 | 1.21 | 9.0 | 1.9 | 9.4 | 92 | 92 | 20 | 19 | 96 | 0 | 0 | 1 | 82 | 19 | C |
| SP | Velasquez, V.Velasquez, Vincent >> | 29 | 2021 | R | 22 | 3 | 9 | 6.30 | .324 | .380 | 1.49 | 8.7 | 4.7 | 9.7 | 94 | 91 | 23 | 49 | 101 | 0 | 0 | 2 | 68 | 20 | C |
| SP | Wacha, M.Wacha, Michael >> | 29 | 2021 | R | 24 | 3 | 5 | 5.05 | .299 | .350 | 1.31 | 9.6 | 2.3 | 8.8 | 124 | 132 | 23 | 31 | 121 | 0 | 0 | 5 | 77 | 19 | C |
| SP | Lopez, J.Lopez, Jorge >> | 28 | 2021 | R | 5 | 3 | 14 | 6.07 | .347 | .400 | 1.64 | 10.6 | 4.2 | 8.3 | 121 | 142 | 21 | 56 | 112 | 0 | 0 | 9 | 66 | 18 | C |
| SP | Allard, K.Allard, Kolby >> | 23 | 2021 | L | 25 | 3 | 12 | 5.41 | .294 | .340 | 1.28 | 9.3 | 2.3 | 7.5 | 124 | 128 | 29 | 31 | 104 | 0 | 0 | 4 | 70 | 18 | C |
| SP | Bundy, D.Bundy, Dylan >> | 29 | 2021 | R | 23 | 2 | 9 | 6.06 | .305 | .360 | 1.37 | 8.9 | 3.4 | 8.4 | 90 | 89 | 20 | 34 | 84 | 0 | 0 | 1 | 71 | 18 | C |
| SP | Foltynewicz, M.Foltynewicz, Michael >> | 29 | 2021 | R | 31 | 2 | 12 | 5.44 | .291 | .340 | 1.26 | 9.0 | 2.3 | 6.3 | 139 | 139 | 35 | 36 | 97 | 0 | 0 | 2 | 88 | 16 | C |