| SP | Schmidt, J.Schmidt, Jason | 30 | Stingers | R | 53.0 | 12 | 12 | 6 | 3 | 2.92 | .300 | 1.25 | 7.3 | 4.0 | 10.3 | 86.1 | 70 | 28 | 28 | 8 | 38 | 98 | 1 | 0 | 0 | 1 | 8 | 3 | 2 | 3.36 |
| SP | Lincecum, T.Lincecum, Tim # $ | 25 | Nuked Hotdogs | R | 52.0 | 12 | 12 | 6 | 3 | 2.88 | .303 | 1.29 | 8.3 | 3.4 | 10.2 | 84.1 | 77 | 30 | 27 | 11 | 32 | 95 | 1 | 0 | 0 | 1 | 10 | 1 | 1 | 3.62 |
| SP | Vazquez, J.Vazquez, Javier # | 33 | Warriors | R | 49.0 | 11 | 11 | 7 | 1 | 4.00 | .280 | 1.13 | 8.8 | 1.5 | 11.2 | 78.2 | 76 | 35 | 35 | 12 | 13 | 97 | 0 | 0 | 0 | 0 | 6 | 3 | 3 | 3.13 |
| SP | Martinez, P.Martinez, Pedro $ | 29 | Miners | R | 47.0 | 12 | 12 | 6 | 5 | 3.58 | .266 | 1.05 | 7.5 | 2.0 | 10.7 | 93.0 | 77 | 38 | 37 | 7 | 21 | 111 | 3 | 0 | 0 | 1 | 7 | 3 | 2 | 2.37 |
| SP | Halladay, R.Halladay, Roy $$ | 28 | Nuked Hotdogs | R | 43.0 | 11 | 11 | 7 | 4 | 3.61 | .320 | 1.36 | 9.3 | 3.0 | 4.6 | 82.1 | 85 | 34 | 33 | 8 | 27 | 42 | 1 | 0 | 0 | 0 | 8 | 4 | 1 | 4.38 |
| SP | Santana, J.Santana, Johan | 25 | Grasshoppers | L | 41.0 | 12 | 12 | 6 | 5 | 3.81 | .290 | 1.22 | 8.4 | 2.6 | 9.5 | 85.0 | 79 | 39 | 36 | 14 | 25 | 90 | 2 | 0 | 0 | 1 | 6 | 0 | 2 | 3.91 |
| SP | Harden, R.Harden, Rich $$ | 27 | Ducks | R | 36.0 | 12 | 12 | 6 | 4 | 3.69 | .312 | 1.30 | 7.8 | 4.0 | 8.9 | 70.2 | 61 | 29 | 29 | 6 | 31 | 69 | 0 | 0 | 0 | 0 | 6 | 4 | 2 | 3.64 |