| SP | Sanchez, A.Sanchez, Anibal | 24 | Cardinals | R | 91 | 28 | 28 | 13 | 11 | 4.12 | .295 | 1.24 | 7.5 | 3.7 | 7.1 | 192.1 | 160 | 93 | 88 | 27 | 79 | 151 | 5 | 0 | 0 | 1 | 17 | 2 | 2 | 4.52 |
| SP | Wainwright, A.Wainwright, Adam | 24 | Bombers | R | 95 | 28 | 28 | 14 | 11 | 3.92 | .291 | 1.22 | 8.4 | 2.6 | 7.0 | 208.2 | 195 | 94 | 91 | 25 | 60 | 161 | 6 | 0 | 0 | 1 | 17 | 2 | 2 | 3.91 |
| SP | McGowan, D.McGowan, Dustin | 23 | 57's | R | 77 | 27 | 27 | 12 | 8 | 4.47 | .308 | 1.32 | 8.5 | 3.4 | 5.6 | 157.0 | 148 | 84 | 78 | 26 | 59 | 97 | 0 | 0 | 0 | 0 | 15 | 3 | 5 | 5.10 |
| RP | Carrasco, H.Carrasco, Hector | 26 | Prospects | R | 83 | 103 | 0 | 15 | 7 | 3.23 | .253 | 1.00 | 6.7 | 2.3 | 6.9 | 189.2 | 140 | 76 | 68 | 20 | 49 | 144 | 0 | 2 | 1 | 0 | 0 | 4 | 4 | 3.69 |
| RP | Takatsu, S.Takatsu, Shingo | 28 | Red Sox | R | 85 | 70 | 0 | 6 | 5 | 1.72 | .222 | 0.82 | 5.0 | 2.4 | 6.9 | 89.0 | 49 | 21 | 17 | 6 | 24 | 68 | 0 | 26 | 2 | 0 | 0 | 3 | 0 | 3.26 |
| CL | Rodriguez, F.Rodriguez, Francisco | 31 | Miller Express | R | 57 | 64 | 0 | 4 | 5 | 4.15 | .318 | 1.35 | 7.5 | 4.8 | 4.5 | 60.2 | 50 | 31 | 28 | 5 | 32 | 30 | 0 | 30 | 6 | 0 | 0 | 3 | 2 | 4.83 |
| CL | Politte, C.Politte, Cliff | 27 | Bulls | R | 95 | 51 | 0 | 3 | 6 | 2.40 | .244 | 0.97 | 6.4 | 2.4 | 9.0 | 48.2 | 34 | 16 | 13 | 5 | 13 | 48 | 0 | 34 | 1 | 0 | 0 | 0 | 1 | 3.17 |
| CL | Papelbon, J.Papelbon, Jonathan | 25 | Millionaires | R | 100 | 60 | 0 | 3 | 3 | 3.28 | .259 | 1.00 | 6.5 | 2.6 | 8.7 | 90.2 | 65 | 34 | 33 | 13 | 26 | 87 | 0 | 28 | 4 | 0 | 0 | 4 | 4 | 3.94 |