| SP | Kershaw, C.Kershaw, Clayton | 28 | Skeeters | L | 99 | 20 | 20 | 11 | 5 | 3.43 | .266 | 1.07 | 7.8 | 1.9 | 8.3 | 152.0 | 131 | 70 | 58 | 15 | 32 | 141 | 5 | 0 | 0 | 1 | 12 | 2 | 0 | 3.10 |
| SP | Johnson, W.Johnson, Walter | 26 | YearOfThePlague | R | 95 | 21 | 21 | 10 | 5 | 2.98 | .279 | 1.14 | 7.7 | 2.5 | 4.8 | 148.0 | 127 | 52 | 49 | 6 | 41 | 79 | 6 | 0 | 0 | 1 | 15 | 4 | 1 | 3.37 |
| SP | Kluber, C.Kluber, Corey # | 31 | YearOfThePlague | R | 90 | 20 | 20 | 10 | 6 | 3.27 | .280 | 1.13 | 8.3 | 2.0 | 8.1 | 145.2 | 133 | 62 | 53 | 10 | 32 | 130 | 6 | 0 | 0 | 1 | 13 | 5 | 5 | 2.87 |
| RP | Benoit, J.Benoit, Joaquin | 33 | Grasshoppers | R | 94 | 56 | 0 | 3 | 0 | 2.32 | .245 | 0.97 | 5.6 | 3.2 | 6.4 | 89.1 | 55 | 26 | 23 | 3 | 32 | 63 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 3.10 |
| CL | Kimbrel, C.Kimbrel, Craig | 24 | Texians | R | 100 | 41 | 0 | 4 | 1 | 3.02 | .277 | 1.10 | 6.1 | 4.0 | 8.8 | 41.2 | 28 | 14 | 14 | 4 | 18 | 40 | 0 | 23 | 2 | 0 | 0 | 2 | 3 | 3.78 |