| SP | Scherzer, M.Scherzer, Max | 34 | Metro | R | 100 | 21 | 21 | 12 | 4 | 1.89 | .263 | 1.06 | 6.8 | 2.7 | 11.2 | 157.0 | 119 | 35 | 33 | 9 | 47 | 195 | 3 | 0 | 0 | 3 | 20 | 2 | 1 | 2.20 |
| SP | Buehler, W.Buehler, Walker | 23 | Nightmares | R | 97 | 21 | 21 | 10 | 6 | 3.20 | .287 | 1.17 | 8.0 | 2.5 | 10.6 | 132.1 | 118 | 49 | 47 | 11 | 37 | 155 | 0 | 0 | 0 | 0 | 14 | 5 | 3 | 2.69 |
| SP | Buchholz, C.Buchholz, Clay | 34 | Prospectors | R | 89 | 20 | 20 | 13 | 5 | 3.57 | .297 | 1.25 | 8.6 | 2.6 | 8.1 | 126.0 | 120 | 53 | 50 | 13 | 37 | 113 | 0 | 0 | 0 | 0 | 13 | 3 | 1 | 3.50 |
| RP | Casilla, S.Casilla, Santiago | 38 | Nightmares | R | 63 | 49 | 0 | 7 | 1 | 3.59 | .347 | 1.51 | 7.6 | 6.2 | 7.6 | 57.2 | 48 | 24 | 23 | 5 | 39 | 48 | 0 | 8 | 2 | 0 | 0 | 5 | 6 | 4.77 |
| CL | Doolittle, S.Doolittle, Sean | 31 | Prospectors | L | 100 | 47 | 0 | 4 | 5 | 3.74 | .271 | 1.09 | 8.0 | 2.0 | 10.4 | 45.2 | 40 | 20 | 19 | 7 | 10 | 52 | 0 | 23 | 5 | 0 | 0 | 1 | 2 | 3.44 |