| SP | Santana, J.Santana, Johan $ | 25 | Red Sox | L | 45.0 | 12 | 12 | 6 | 3 | 3.46 | .299 | 1.27 | 7.2 | 4.3 | 11.1 | 78.0 | 62 | 30 | 30 | 14 | 37 | 96 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 4.33 |
| SP | Pettitte, A.Pettitte, Andy # | 33 | Bronx Bombers | L | 43.0 | 12 | 12 | 8 | 2 | 4.20 | .333 | 1.49 | 10.3 | 3.2 | 4.5 | 70.2 | 80 | 37 | 33 | 12 | 25 | 35 | 0 | 0 | 0 | 0 | 7 | 1 | 3 | 5.34 |
| SP | Martinez, P.Martinez, Pedro | 29 | Bronx Bombers | R | 40.0 | 12 | 12 | 6 | 3 | 3.74 | .289 | 1.22 | 7.5 | 3.5 | 8.9 | 67.1 | 56 | 28 | 28 | 9 | 26 | 66 | 1 | 0 | 0 | 1 | 7 | 0 | 3 | 3.94 |
| SP | Hernandez, F.Hernandez, Felix | 19 | Skeletons | R | 40.0 | 12 | 12 | 5 | 5 | 3.10 | .293 | 1.20 | 7.4 | 3.3 | 6.8 | 87.0 | 72 | 37 | 30 | 10 | 32 | 66 | 2 | 0 | 0 | 0 | 8 | 4 | 1 | 4.22 |
| SP | Zambrano, C.Zambrano, Carlos | 24 | McKnights | R | 39.0 | 11 | 11 | 7 | 3 | 4.21 | .317 | 1.33 | 8.1 | 4.0 | 7.3 | 72.2 | 65 | 35 | 34 | 10 | 32 | 58 | 0 | 0 | 0 | 0 | 6 | 4 | 3 | 4.69 |
| SP | Carpenter, C.Carpenter, Chris | 34 | Bronx Bombers | R | 38.0 | 12 | 12 | 6 | 2 | 4.05 | .329 | 1.46 | 10.4 | 2.9 | 5.6 | 66.2 | 76 | 31 | 30 | 10 | 21 | 41 | 2 | 0 | 0 | 1 | 6 | 1 | 2 | 4.73 |
| SP | Lincecum, T.Lincecum, Tim | 25 | Sharks | R | 38.0 | 12 | 12 | 5 | 4 | 3.61 | .298 | 1.27 | 7.6 | 3.9 | 10.2 | 87.1 | 73 | 36 | 35 | 6 | 38 | 99 | 0 | 0 | 0 | 0 | 7 | 0 | 4 | 2.93 |