| SP | Arrieta, J.Arrieta, Jake # | 29 | Yardbirds | R | 92 | 21 | 21 | 12 | 8 | 3.10 | .278 | 1.14 | 7.9 | 2.4 | 7.4 | 151.0 | 132 | 59 | 52 | 11 | 40 | 124 | 4 | 0 | 0 | 2 | 15 | 2 | 2 | 3.14 |
| SP | Koufax, S.Koufax, Sandy # | 30 | Mules | L | 97 | 22 | 22 | 10 | 6 | 3.31 | .291 | 1.21 | 7.7 | 3.2 | 7.5 | 163.0 | 139 | 62 | 60 | 16 | 58 | 135 | 4 | 0 | 0 | 1 | 14 | 4 | 3 | 3.76 |
| CL | Benitez, A.Benitez, Armando | 32 | Quakers | R | 82 | 44 | 0 | 2 | 1 | 3.59 | .301 | 1.29 | 8.6 | 3.2 | 6.4 | 42.2 | 40 | 18 | 17 | 2 | 15 | 30 | 0 | 29 | 4 | 0 | 0 | 0 | 0 | 3.26 |
| CL | Eckersley, D.Eckersley, Dennis | 36 | Bunch | R | 87 | 52 | 0 | 2 | 6 | 2.63 | .278 | 1.12 | 8.5 | 1.7 | 7.2 | 54.2 | 51 | 17 | 16 | 1 | 10 | 43 | 0 | 29 | 3 | 0 | 0 | 2 | 0 | 2.31 |
| CL | Papelbon, J.Papelbon, Jonathan | 27 | All Stars | R | 92 | 44 | 0 | 4 | 4 | 4.11 | .317 | 1.35 | 8.6 | 3.5 | 8.2 | 46.0 | 44 | 21 | 21 | 5 | 18 | 42 | 0 | 20 | 7 | 0 | 0 | 2 | 0 | 3.89 |