| SP | Duchscherer, J.Duchscherer, Justin | 31 | Giants | R | 85 | 22 | 22 | 12 | 4 | 3.36 | .309 | 1.31 | 8.3 | 3.5 | 6.3 | 150.0 | 138 | 63 | 56 | 16 | 59 | 105 | 1 | 0 | 0 | 1 | 16 | 4 | 5 | 4.25 |
| SP | Buehrle, M.Buehrle, Mark # | 22 | Snakes | L | 68 | 22 | 22 | 12 | 4 | 3.93 | .291 | 1.21 | 8.4 | 2.5 | 6.7 | 155.2 | 145 | 69 | 68 | 18 | 43 | 115 | 6 | 0 | 0 | 3 | 13 | 4 | 3 | 3.94 |
| SU | Valverde, J.Valverde, Jose | 24 | Ants | R | 79 | 44 | 0 | 3 | 3 | 2.90 | .294 | 1.19 | 6.6 | 4.2 | 11.9 | 49.2 | 36 | 17 | 16 | 6 | 23 | 65 | 0 | 12 | 1 | 0 | 0 | 3 | 3 | 3.53 |
| CL | Rivera, M.Rivera, Mariano | 39 | Tanks | R | 96 | 44 | 0 | 2 | 6 | 1.85 | .274 | 1.09 | 8.1 | 1.9 | 10.1 | 48.2 | 43 | 10 | 10 | 2 | 10 | 54 | 0 | 26 | 2 | 0 | 0 | 2 | 0 | 2.04 |
| CL | Benitez, A.Benitez, Armando | 32 | Vikings | R | 91 | 48 | 0 | 1 | 0 | 4.53 | .308 | 1.29 | 7.8 | 4.0 | 7.4 | 45.2 | 39 | 23 | 23 | 8 | 20 | 37 | 0 | 26 | 0 | 0 | 0 | 2 | 0 | 5.13 |