| SP | Kershaw, C.Kershaw, Clayton | 28 | Mutuals | L | 99.0 | 16 | 16 | 10 | 0 | 2.29 | .243 | 0.95 | 6.9 | 1.7 | 8.3 | 121.2 | 93 | 31 | 31 | 13 | 23 | 112 | 2 | 0 | 0 | 2 | 14 | 1 | 3 | 3.14 |
| SP | Koufax, S.Koufax, Sandy # | 30 | Pigs | L | 73.0 | 16 | 16 | 8 | 4 | 3.08 | .261 | 1.04 | 7.5 | 1.9 | 8.9 | 125.2 | 104 | 43 | 43 | 12 | 27 | 124 | 5 | 0 | 0 | 0 | 11 | 2 | 1 | 2.96 |
| SP | Mathewson, C.Mathewson, Christy $$ | 28 | Bambinos | R | 70.0 | 15 | 15 | 8 | 5 | 2.95 | .242 | 0.95 | 7.1 | 1.4 | 4.5 | 119.0 | 94 | 41 | 39 | 9 | 19 | 59 | 7 | 0 | 0 | 2 | 9 | 1 | 2 | 3.50 |
| SP | Cicotte, E.Cicotte, Eddie | 33 | Tigers | R | 65.0 | 15 | 15 | 10 | 3 | 4.08 | .297 | 1.23 | 8.4 | 2.7 | 5.0 | 114.2 | 107 | 52 | 52 | 14 | 34 | 63 | 5 | 0 | 0 | 0 | 9 | 4 | 0 | 4.49 |
| SP | Martinez, P.Martinez, Pedro # $ | 29 | Heroes | R | 62.0 | 16 | 16 | 7 | 6 | 3.62 | .292 | 1.22 | 9.1 | 2.0 | 10.1 | 126.2 | 127 | 52 | 51 | 13 | 28 | 141 | 6 | 0 | 0 | 3 | 10 | 2 | 1 | 2.82 |
| SP | Scherzer, M.Scherzer, Max # | 33 | Bulldogs | R | 54.0 | 16 | 16 | 8 | 6 | 3.85 | .263 | 1.04 | 6.2 | 3.2 | 8.8 | 114.2 | 79 | 49 | 49 | 19 | 40 | 112 | 2 | 0 | 0 | 1 | 10 | 4 | 0 | 4.36 |
| SP | Leonard, D.Leonard, Dutch $$ | 22 | Bambinos | L | 54.0 | 16 | 16 | 7 | 2 | 3.54 | .313 | 1.34 | 7.8 | 4.4 | 6.5 | 101.2 | 87 | 45 | 40 | 9 | 49 | 73 | 1 | 0 | 0 | 0 | 7 | 3 | 2 | 4.26 |