| SP | Martinez, P.Martinez, Pedro $ | 29 | Patriots | R | 70.0 | 15 | 15 | 9 | 3 | 3.12 | .273 | 1.08 | 6.7 | 3.0 | 9.9 | 104.0 | 77 | 38 | 36 | 15 | 35 | 114 | 1 | 0 | 0 | 0 | 10 | 5 | 1 | 3.84 |
| SP | Halladay, R.Halladay, Roy | 28 | Bombers | R | 64.0 | 15 | 15 | 7 | 4 | 2.90 | .280 | 1.16 | 8.3 | 2.1 | 6.3 | 115.0 | 106 | 38 | 37 | 8 | 27 | 80 | 5 | 0 | 0 | 0 | 11 | 1 | 2 | 3.24 |
| SP | Mussina, M.Mussina, Mike # | 33 | Warriors | R | 62.0 | 15 | 15 | 10 | 3 | 4.10 | .287 | 1.16 | 8.4 | 2.1 | 8.1 | 105.1 | 98 | 51 | 48 | 17 | 24 | 94 | 1 | 0 | 0 | 0 | 9 | 5 | 3 | 4.14 |
| SP | Clemens, R.Clemens, Roger | 43 | Plunder | R | 53.0 | 15 | 15 | 8 | 4 | 3.59 | .317 | 1.37 | 9.0 | 3.4 | 7.9 | 97.2 | 97 | 40 | 39 | 8 | 37 | 85 | 0 | 0 | 0 | 0 | 10 | 2 | 3 | 3.53 |
| SP | Santana, J.Santana, Johan | 25 | Cats | L | 47.0 | 15 | 15 | 6 | 4 | 3.53 | .268 | 1.09 | 7.4 | 2.4 | 8.0 | 104.2 | 86 | 44 | 41 | 16 | 28 | 93 | 1 | 0 | 0 | 1 | 11 | 1 | 2 | 4.05 |
| SP | Schmidt, J.Schmidt, Jason # | 30 | Red Sox | R | 45.0 | 15 | 15 | 7 | 4 | 4.13 | .292 | 1.22 | 8.3 | 2.7 | 8.4 | 100.1 | 92 | 49 | 46 | 17 | 30 | 93 | 2 | 0 | 0 | 0 | 9 | 2 | 6 | 4.31 |
| SP | Duchscherer, J.Duchscherer, Justin $$ | 31 | Warriors | R | 42.0 | 15 | 15 | 7 | 4 | 4.02 | .298 | 1.22 | 8.8 | 2.3 | 5.8 | 100.2 | 98 | 47 | 45 | 17 | 25 | 64 | 0 | 0 | 0 | 0 | 10 | 5 | 0 | 4.83 |