| SP | Leonard, D.Leonard, Dutch | 22 | Peppers | L | 91 | 29 | 29 | 18 | 6 | 2.12 | .251 | 1.00 | 6.0 | 2.9 | 5.0 | 208.0 | 139 | 51 | 49 | 11 | 68 | 115 | 5 | 0 | 0 | 3 | 26 | 2 | 3 | 3.59 |
| SP | Scherzer, M.Scherzer, Max | 33 | Gladiators | R | 95 | 30 | 30 | 12 | 10 | 3.93 | .286 | 1.16 | 6.9 | 3.6 | 7.6 | 190.0 | 145 | 91 | 83 | 19 | 76 | 160 | 0 | 0 | 0 | 0 | 20 | 7 | 6 | 3.93 |
| SP | Johnson, W.Johnson, Walter | 26 | Peppers | R | 95 | 30 | 30 | 13 | 8 | 3.84 | .282 | 1.15 | 8.5 | 1.9 | 5.1 | 192.1 | 181 | 83 | 82 | 18 | 41 | 108 | 4 | 0 | 0 | 4 | 16 | 5 | 2 | 3.81 |
| SP | Martinez, P.Martinez, Pedro | 29 | Osprey | R | 100 | 30 | 30 | 12 | 12 | 4.34 | .326 | 1.41 | 9.0 | 3.7 | 8.9 | 201.1 | 200 | 112 | 97 | 18 | 83 | 198 | 1 | 0 | 0 | 1 | 15 | 9 | 1 | 3.57 |
| RP | Kimbrel, C.Kimbrel, Craig | 24 | Peppers | R | 100 | 77 | 0 | 7 | 3 | 1.82 | .245 | 0.96 | 5.0 | 3.6 | 10.3 | 109.0 | 61 | 24 | 22 | 5 | 44 | 125 | 0 | 11 | 4 | 0 | 0 | 1 | 8 | 2.54 |
| CL | Chapman, A.Chapman, Aroldis | 26 | Monarchs | L | 94 | 57 | 0 | 3 | 6 | 4.79 | .272 | 1.08 | 6.3 | 3.5 | 9.3 | 56.1 | 39 | 30 | 30 | 13 | 22 | 58 | 0 | 32 | 5 | 0 | 0 | 2 | 3 | 5.23 |
| CL | Doolittle, S.Doolittle, Sean | 31 | Osprey | L | 99 | 54 | 0 | 2 | 4 | 4.03 | .287 | 1.21 | 8.3 | 2.6 | 9.4 | 51.1 | 47 | 25 | 23 | 4 | 15 | 53 | 0 | 34 | 7 | 0 | 0 | 0 | 1 | 2.82 |