| SP | Martinez, P.Martinez, Pedro | 29 | Crabs | R | 100 | 29 | 29 | 19 | 4 | 2.78 | .249 | 0.99 | 6.7 | 2.3 | 9.6 | 213.2 | 158 | 68 | 66 | 29 | 54 | 228 | 9 | 0 | 0 | 4 | 20 | 1 | 1 | 3.40 |
| SP | Johnson, R.Johnson, Randy | 38 | Plunder | L | 97 | 29 | 29 | 13 | 10 | 3.32 | .315 | 1.34 | 9.0 | 3.0 | 10.5 | 214.1 | 215 | 87 | 79 | 19 | 72 | 250 | 5 | 0 | 0 | 3 | 19 | 9 | 4 | 2.95 |
| SP | Halladay, R.Halladay, Roy # | 28 | Beavers | R | 86 | 28 | 28 | 14 | 10 | 3.26 | .265 | 1.05 | 7.6 | 1.8 | 7.0 | 218.0 | 185 | 84 | 79 | 25 | 43 | 170 | 5 | 0 | 0 | 2 | 17 | 8 | 8 | 3.63 |
| SP | Lincecum, T.Lincecum, Tim | 25 | Beavers | R | 92 | 29 | 29 | 11 | 13 | 3.75 | .318 | 1.35 | 8.6 | 3.5 | 8.6 | 206.1 | 197 | 94 | 86 | 22 | 81 | 196 | 5 | 0 | 0 | 1 | 19 | 10 | 10 | 3.81 |
| CL | Papelbon, J.Papelbon, Jonathan | 26 | Ninjas | R | 94 | 49 | 0 | 5 | 3 | 1.67 | .250 | 1.00 | 7.5 | 1.5 | 8.5 | 54.0 | 45 | 10 | 10 | 3 | 9 | 51 | 0 | 28 | 1 | 0 | 0 | 0 | 0 | 2.33 |