| SP | Johnson, R.Johnson, Randy | 38 | Falcons | L | 54.0 | 13 | 13 | 7 | 2 | 3.63 | .295 | 1.23 | 7.6 | 3.5 | 10.4 | 89.1 | 75 | 37 | 36 | 9 | 35 | 103 | 1 | 0 | 0 | 1 | 7 | 2 | 6 | 3.25 |
| SP | Buehrle, M.Buehrle, Mark # | 22 | Ducks | L | 50.0 | 12 | 12 | 7 | 4 | 3.61 | .288 | 1.18 | 8.2 | 2.4 | 7.0 | 92.1 | 84 | 38 | 37 | 13 | 25 | 72 | 2 | 0 | 0 | 1 | 7 | 3 | 3 | 4.18 |
| SP | Lincecum, T.Lincecum, Tim # | 25 | Crabs | R | 47.0 | 13 | 13 | 5 | 3 | 3.29 | .298 | 1.24 | 7.9 | 3.4 | 9.8 | 95.2 | 83 | 38 | 35 | 12 | 36 | 103 | 2 | 0 | 0 | 1 | 8 | 3 | 1 | 3.71 |
| SP | Schilling, C.Schilling, Curt | 36 | Ol' Brewers | R | 46.0 | 13 | 13 | 5 | 4 | 3.35 | .278 | 1.14 | 8.5 | 1.7 | 9.4 | 99.1 | 94 | 37 | 37 | 10 | 19 | 103 | 2 | 0 | 0 | 1 | 8 | 2 | 1 | 2.87 |
| SP | Martinez, P.Martinez, Pedro | 29 | Team | R | 44.0 | 13 | 13 | 5 | 4 | 3.67 | .276 | 1.13 | 8.3 | 1.9 | 10.1 | 98.0 | 90 | 46 | 40 | 13 | 21 | 110 | 4 | 0 | 0 | 0 | 6 | 1 | 1 | 3.15 |
| SP | Duchscherer, J.Duchscherer, Justin | 31 | Serpents | R | 41.0 | 13 | 13 | 4 | 3 | 3.02 | .251 | 1.00 | 6.6 | 2.4 | 6.8 | 86.1 | 63 | 30 | 29 | 8 | 23 | 65 | 2 | 0 | 0 | 2 | 9 | 1 | 0 | 3.53 |