| SP | Buehrle, M.Buehrle, Mark # | 22 | Ducks | L | 70.0 | 14 | 14 | 9 | 4 | 3.18 | .271 | 1.09 | 7.5 | 2.3 | 6.5 | 110.1 | 92 | 40 | 39 | 13 | 28 | 80 | 4 | 0 | 0 | 1 | 9 | 3 | 3 | 3.93 |
| SP | Lincecum, T.Lincecum, Tim # | 25 | Crabs | R | 58.0 | 15 | 15 | 6 | 3 | 3.15 | .298 | 1.24 | 7.9 | 3.3 | 9.6 | 111.1 | 97 | 42 | 39 | 13 | 41 | 119 | 2 | 0 | 0 | 1 | 10 | 4 | 1 | 3.59 |
| SP | Johnson, R.Johnson, Randy | 38 | Falcons | L | 56.0 | 15 | 15 | 8 | 3 | 3.97 | .305 | 1.29 | 8.2 | 3.5 | 10.5 | 99.2 | 90 | 45 | 44 | 10 | 39 | 115 | 1 | 0 | 0 | 1 | 8 | 2 | 6 | 3.23 |
| SP | Halladay, R.Halladay, Roy | 28 | Falcons | R | 55.0 | 15 | 15 | 7 | 4 | 3.70 | .288 | 1.18 | 8.2 | 2.4 | 6.8 | 112.0 | 102 | 50 | 46 | 20 | 30 | 85 | 5 | 0 | 0 | 0 | 10 | 4 | 4 | 4.71 |
| SP | Martinez, P.Martinez, Pedro | 29 | Team | R | 49.0 | 15 | 15 | 6 | 4 | 3.86 | .285 | 1.19 | 8.4 | 2.3 | 9.9 | 109.2 | 102 | 53 | 47 | 14 | 28 | 120 | 4 | 0 | 0 | 0 | 7 | 1 | 1 | 3.27 |
| SP | Schilling, C.Schilling, Curt | 36 | Ol' Brewers | R | 48.0 | 15 | 15 | 6 | 5 | 3.67 | .288 | 1.20 | 8.8 | 2.0 | 9.0 | 112.2 | 110 | 46 | 46 | 14 | 25 | 112 | 2 | 0 | 0 | 1 | 9 | 2 | 1 | 3.35 |