| SP | Santana, J.Santana, Johan | 25 | Nightmares | L | 100 | 32 | 32 | 14 | 11 | 3.67 | .280 | 1.12 | 7.6 | 2.5 | 9.8 | 233.0 | 196 | 99 | 95 | 25 | 65 | 254 | 4 | 0 | 0 | 2 | 22 | 11 | 4 | 3.19 |
| SP | Martinez, P.Martinez, Pedro | 29 | Fighting Pigs | R | 100 | 33 | 33 | 19 | 5 | 3.46 | .286 | 1.17 | 7.9 | 2.6 | 9.6 | 257.1 | 226 | 113 | 99 | 27 | 75 | 273 | 5 | 0 | 0 | 1 | 18 | 8 | 6 | 3.21 |
| SP | Lincecum, T.Lincecum, Tim # | 25 | Lions | R | 92 | 32 | 32 | 19 | 8 | 3.40 | .290 | 1.20 | 7.9 | 2.9 | 9.3 | 241.0 | 211 | 92 | 91 | 31 | 77 | 248 | 4 | 0 | 0 | 2 | 19 | 7 | 6 | 3.66 |
| RP | Balfour, G.Balfour, Grant | 31 | Elephants | R | 90 | 85 | 0 | 11 | 4 | 3.29 | .296 | 1.20 | 6.1 | 4.7 | 8.8 | 104.0 | 71 | 42 | 38 | 11 | 54 | 102 | 0 | 8 | 5 | 0 | 0 | 6 | 3 | 4.14 |
| CL | Soriano, R.Soriano, Rafael | 24 | GermanMechanics | R | 97 | 81 | 0 | 9 | 5 | 3.40 | .278 | 1.12 | 7.0 | 3.1 | 9.2 | 92.2 | 72 | 39 | 35 | 8 | 32 | 94 | 0 | 42 | 6 | 0 | 0 | 3 | 0 | 3.23 |