| SP | Johnson, R.Johnson, Randy | 41 | D-Backs | L | 80.0 | 12 | 12 | 8 | 2 | 2.13 | .259 | 1.03 | 7.6 | 1.7 | 6.6 | 101.1 | 85 | 24 | 24 | 7 | 19 | 74 | 6 | 0 | 0 | 0 | 11 | 2 | 2 | 3.06 |
| SP | Scherzer, M.Scherzer, Max | 37 | Senators | R | 63.0 | 13 | 13 | 8 | 2 | 3.02 | .268 | 1.10 | 8.2 | 1.8 | 9.3 | 86.1 | 78 | 31 | 29 | 8 | 17 | 89 | 1 | 0 | 0 | 1 | 8 | 0 | 0 | 2.73 |
| SP | Flaherty, J.Flaherty, Jack | 23 | Cardinals | R | 57.0 | 12 | 12 | 8 | 1 | 3.38 | .253 | 1.01 | 7.3 | 1.9 | 9.4 | 72.0 | 58 | 27 | 27 | 11 | 15 | 75 | 0 | 0 | 0 | 0 | 9 | 0 | 2 | 3.53 |
| SP | Chamberlain, E.Chamberlain, Elton | 21 | Cardinals | R | 56.0 | 13 | 13 | 8 | 2 | 3.80 | .304 | 1.31 | 9.2 | 2.6 | 5.3 | 90.0 | 92 | 44 | 38 | 10 | 26 | 53 | 4 | 0 | 0 | 0 | 8 | 0 | 0 | 4.13 |
| SP | Martinez, P.Martinez, Pedro | 26 | Senators | R | 39.0 | 13 | 13 | 5 | 5 | 4.03 | .297 | 1.26 | 7.6 | 3.7 | 7.8 | 105.0 | 89 | 49 | 47 | 10 | 43 | 91 | 5 | 0 | 0 | 1 | 6 | 1 | 2 | 3.76 |
| SP | Siebert, S.Siebert, Sonny | 31 | Guardians | R | 38.0 | 14 | 0 | 6 | 2 | 4.03 | .290 | 1.21 | 7.3 | 3.6 | 6.9 | 76.0 | 62 | 34 | 34 | 11 | 30 | 58 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.58 |