| SP | Williams, S.Williams, Stan | 28 | Tigers | R | 131.0 | 24 | 24 | 15 | 6 | 2.21 | .250 | 0.97 | 6.3 | 2.5 | 5.8 | 171.0 | 119 | 45 | 42 | 12 | 47 | 111 | 4 | 0 | 0 | 2 | 19 | 5 | 3 | 3.53 |
| SP | Marichal, J.Marichal, Juan | 27 | Red Sox | R | 78.0 | 24 | 24 | 11 | 10 | 4.03 | .293 | 1.22 | 8.0 | 3.0 | 4.4 | 183.1 | 162 | 84 | 82 | 22 | 62 | 89 | 13 | 0 | 0 | 4 | 11 | 4 | 8 | 4.67 |
| SP | DeBusschere, D.DeBusschere, Dave | 30 | White Sox | R | 78.0 | 24 | 24 | 10 | 6 | 2.64 | .267 | 1.08 | 7.4 | 2.2 | 5.0 | 133.0 | 110 | 43 | 39 | 10 | 33 | 74 | 0 | 0 | 0 | 0 | 8 | 2 | 8 | 3.65 |
| SP | Newcombe, D.Newcombe, Don # | 30 | Indians | R | 67.0 | 24 | 24 | 11 | 8 | 4.01 | .286 | 1.15 | 9.0 | 1.4 | 4.6 | 163.2 | 163 | 75 | 73 | 23 | 26 | 83 | 4 | 0 | 0 | 1 | 14 | 8 | 3 | 4.44 |
| SP | Hunter, C.Hunter, Catfish | 28 | A's | R | 67.0 | 24 | 24 | 10 | 10 | 3.44 | .280 | 1.14 | 8.6 | 1.7 | 5.7 | 162.0 | 154 | 70 | 62 | 19 | 30 | 102 | 1 | 0 | 0 | 0 | 15 | 5 | 2 | 3.91 |
| SP | Mahaffey, A.Mahaffey, Art | 26 | A's | R | 66.0 | 24 | 24 | 11 | 13 | 4.15 | .289 | 1.17 | 8.3 | 2.3 | 5.0 | 182.1 | 167 | 88 | 84 | 23 | 47 | 102 | 12 | 0 | 0 | 0 | 11 | 8 | 2 | 4.43 |