| SP | Johnson, R.Johnson, Randy | 41 | Blues | L | 84 | 26 | 26 | 15 | 7 | 2.87 | .268 | 1.09 | 6.6 | 3.2 | 7.1 | 188.0 | 137 | 66 | 60 | 14 | 67 | 148 | 5 | 0 | 0 | 3 | 18 | 2 | 4 | 3.49 |
| SP | Johnson, W.Johnson, Walter | 26 | Homers | R | 95 | 28 | 28 | 13 | 9 | 2.74 | .246 | 0.97 | 7.0 | 1.7 | 4.3 | 229.2 | 178 | 80 | 70 | 14 | 44 | 110 | 10 | 0 | 0 | 2 | 18 | 3 | 7 | 3.45 |
| SP | Scherzer, M.Scherzer, Max | 33 | Eagles | R | 95 | 28 | 28 | 15 | 8 | 3.43 | .299 | 1.25 | 7.2 | 4.0 | 9.3 | 186.1 | 149 | 71 | 71 | 11 | 83 | 192 | 0 | 0 | 0 | 0 | 22 | 7 | 7 | 3.16 |
| RP | Chapman, A.Chapman, Aroldis | 26 | Royal Giants | L | 93 | 67 | 0 | 4 | 4 | 1.54 | .243 | 0.94 | 4.5 | 4.1 | 11.2 | 93.1 | 46 | 17 | 16 | 6 | 42 | 116 | 0 | 12 | 1 | 0 | 0 | 2 | 4 | 2.76 |
| RP | Betances, D.Betances, Dellin | 26 | Outlaws | R | 94 | 62 | 0 | 11 | 1 | 1.76 | .235 | 0.92 | 4.8 | 3.5 | 9.0 | 71.2 | 38 | 14 | 14 | 3 | 28 | 71 | 0 | 2 | 0 | 0 | 0 | 0 | 4 | 2.73 |
| RP | Eckersley, D.Eckersley, Dennis | 36 | Royal Giants | R | 88 | 58 | 0 | 6 | 5 | 1.81 | .230 | 0.90 | 7.3 | 0.9 | 7.2 | 84.2 | 68 | 20 | 17 | 3 | 8 | 67 | 0 | 7 | 4 | 0 | 0 | 0 | 0 | 2.15 |
| CL | Kimbrel, C.Kimbrel, Craig | 24 | Blues | R | 100 | 54 | 0 | 1 | 2 | 2.72 | .245 | 0.94 | 6.1 | 2.4 | 9.8 | 59.2 | 40 | 18 | 18 | 9 | 16 | 64 | 0 | 35 | 3 | 0 | 0 | 2 | 3 | 3.73 |