| SP | Johnson, R.Johnson, Randy | 41 | Blues | L | 84 | 24 | 24 | 14 | 6 | 2.80 | .266 | 1.07 | 6.3 | 3.3 | 7.0 | 173.1 | 122 | 59 | 54 | 13 | 64 | 134 | 5 | 0 | 0 | 3 | 17 | 2 | 4 | 3.57 |
| SP | Johnson, W.Johnson, Walter | 26 | Homers | R | 95 | 26 | 26 | 12 | 8 | 2.79 | .248 | 0.97 | 7.1 | 1.7 | 4.2 | 212.2 | 167 | 73 | 66 | 13 | 40 | 100 | 8 | 0 | 0 | 2 | 17 | 3 | 7 | 3.46 |
| SP | Scherzer, M.Scherzer, Max | 33 | Eagles | R | 95 | 26 | 26 | 15 | 6 | 3.41 | .301 | 1.25 | 7.1 | 4.3 | 9.6 | 171.2 | 134 | 65 | 65 | 8 | 81 | 183 | 0 | 0 | 0 | 0 | 21 | 7 | 6 | 3.01 |
| RP | Chapman, A.Chapman, Aroldis | 26 | Royal Giants | L | 93 | 62 | 0 | 4 | 3 | 1.55 | .243 | 0.94 | 4.4 | 4.0 | 11.1 | 87.1 | 43 | 16 | 15 | 5 | 39 | 107 | 0 | 11 | 0 | 0 | 0 | 2 | 4 | 2.70 |
| RP | Betances, D.Betances, Dellin | 26 | Outlaws | R | 94 | 59 | 0 | 11 | 1 | 1.85 | .239 | 0.94 | 4.9 | 3.6 | 8.9 | 68.0 | 37 | 14 | 14 | 3 | 27 | 67 | 0 | 2 | 0 | 0 | 0 | 0 | 4 | 2.79 |
| RP | Eckersley, D.Eckersley, Dennis | 36 | Royal Giants | R | 88 | 55 | 0 | 6 | 5 | 1.94 | .236 | 0.93 | 7.5 | 0.9 | 7.2 | 78.2 | 65 | 20 | 17 | 3 | 8 | 62 | 0 | 7 | 3 | 0 | 0 | 0 | 0 | 2.22 |
| CL | Kimbrel, C.Kimbrel, Craig | 24 | Blues | R | 100 | 51 | 0 | 1 | 2 | 2.70 | .251 | 0.97 | 6.3 | 2.6 | 9.8 | 56.2 | 39 | 17 | 17 | 8 | 16 | 61 | 0 | 32 | 3 | 0 | 0 | 2 | 3 | 3.64 |