| SP | Mathewson, C.Mathewson, Christy | 29 | Bees | R | 86 | 33 | 33 | 17 | 9 | 2.90 | .272 | 1.10 | 7.8 | 2.1 | 4.3 | 267.1 | 232 | 99 | 86 | 19 | 63 | 129 | 13 | 0 | 0 | 4 | 22 | 5 | 0 | 3.72 |
| SP | Kershaw, C.Kershaw, Clayton | 28 | Scooters | L | 99 | 33 | 33 | 14 | 9 | 2.50 | .228 | 0.87 | 6.2 | 1.6 | 8.1 | 269.2 | 186 | 80 | 75 | 21 | 49 | 243 | 11 | 0 | 0 | 4 | 28 | 4 | 4 | 2.80 |
| SP | Martinez, P.Martinez, Pedro | 29 | Bees | R | 100 | 31 | 31 | 11 | 11 | 3.36 | .293 | 1.23 | 7.9 | 3.1 | 8.8 | 228.0 | 201 | 91 | 85 | 16 | 79 | 223 | 2 | 0 | 0 | 1 | 21 | 4 | 4 | 3.05 |
| RP | Papelbon, J.Papelbon, Jonathan | 27 | Sockeyes | R | 93 | 77 | 0 | 6 | 1 | 2.10 | .213 | 0.79 | 4.6 | 2.6 | 8.1 | 81.1 | 41 | 19 | 19 | 3 | 23 | 73 | 0 | 15 | 1 | 0 | 0 | 2 | 0 | 2.60 |
| RP | Benoit, J.Benoit, Joaquin | 33 | Scooters | R | 95 | 81 | 0 | 4 | 3 | 2.10 | .245 | 0.95 | 6.5 | 2.1 | 8.6 | 102.2 | 74 | 24 | 24 | 4 | 24 | 97 | 0 | 12 | 4 | 0 | 0 | 2 | 2 | 2.37 |
| CL | Doolittle, S.Doolittle, Sean | 31 | Sockeyes | L | 98 | 67 | 0 | 4 | 4 | 2.14 | .270 | 1.07 | 6.5 | 3.2 | 8.2 | 71.1 | 51 | 18 | 17 | 4 | 25 | 65 | 0 | 36 | 5 | 0 | 0 | 3 | 3 | 3.08 |