| SP | Kershaw, C.Kershaw, Clayton | 28 | Twins | L | 54.0 | 9 | 9 | 6 | 1 | 2.20 | .267 | 1.08 | 7.3 | 2.5 | 8.6 | 69.2 | 56 | 22 | 17 | 5 | 19 | 66 | 0 | 0 | 0 | 0 | 7 | 1 | 4 | 2.90 |
| SP | Koufax, S.Koufax, Sandy # | 30 | Twins | L | 48.0 | 9 | 9 | 6 | 3 | 3.06 | .243 | 0.95 | 7.3 | 1.3 | 8.2 | 70.2 | 57 | 24 | 24 | 8 | 10 | 64 | 4 | 0 | 0 | 1 | 6 | 1 | 2 | 3.13 |
| SP | Gonsolin, T.Gonsolin, Tony | 28 | Twins | R | 42.0 | 9 | 9 | 5 | 1 | 2.28 | .275 | 1.14 | 7.0 | 3.3 | 6.2 | 55.1 | 43 | 16 | 14 | 3 | 20 | 38 | 0 | 0 | 0 | 0 | 5 | 0 | 3 | 3.42 |
| SP | Verlander, J.Verlander, Justin | 39 | Colt .45s | R | 41.0 | 9 | 9 | 6 | 2 | 3.36 | .300 | 1.24 | 7.3 | 3.8 | 10.1 | 59.0 | 48 | 22 | 22 | 6 | 25 | 66 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 3.51 |
| SP | Scherzer, M.Scherzer, Max | 29 | Legends | R | 40.0 | 9 | 9 | 5 | 3 | 2.53 | .286 | 1.19 | 8.3 | 2.4 | 7.9 | 64.0 | 59 | 21 | 18 | 3 | 17 | 56 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 2.70 |
| SP | Mathewson, C.Mathewson, Christy # | 28 | Sock Exchange | R | 31.0 | 9 | 9 | 5 | 3 | 3.71 | .281 | 1.17 | 9.2 | 1.5 | 5.3 | 60.2 | 61 | 33 | 25 | 6 | 10 | 35 | 1 | 0 | 0 | 1 | 6 | 0 | 2 | 3.63 |