| SP | Halladay, R.Halladay, Roy | 28 | Monarchs | R | 87 | 22 | 22 | 11 | 8 | 3.16 | .270 | 1.08 | 7.6 | 2.2 | 5.2 | 159.2 | 135 | 64 | 56 | 14 | 38 | 92 | 8 | 0 | 0 | 1 | 16 | 4 | 3 | 3.78 |
| SP | Lincecum, T.Lincecum, Tim | 25 | Wolves | R | 92 | 23 | 23 | 12 | 8 | 3.71 | .323 | 1.41 | 9.5 | 3.2 | 10.4 | 153.0 | 161 | 65 | 63 | 17 | 54 | 177 | 2 | 0 | 0 | 1 | 14 | 4 | 4 | 3.27 |
| SP | Johnson, R.Johnson, Randy | 38 | Gorillas | L | 97 | 23 | 23 | 12 | 7 | 3.91 | .309 | 1.31 | 8.7 | 3.2 | 10.1 | 158.2 | 152 | 72 | 69 | 18 | 56 | 178 | 4 | 0 | 0 | 0 | 14 | 5 | 2 | 3.39 |
| SP | Santana, J.Santana, Johan | 25 | Bucs | L | 100 | 23 | 23 | 12 | 7 | 3.78 | .283 | 1.16 | 7.6 | 2.8 | 8.0 | 152.1 | 129 | 67 | 64 | 21 | 47 | 135 | 4 | 0 | 0 | 3 | 11 | 4 | 8 | 4.03 |
| SP | Duchscherer, J.Duchscherer, Justin | 31 | Bees | R | 84 | 22 | 22 | 11 | 7 | 2.91 | .245 | 0.97 | 6.7 | 2.0 | 6.2 | 163.2 | 122 | 55 | 53 | 13 | 36 | 113 | 3 | 0 | 0 | 2 | 15 | 1 | 3 | 3.33 |
| RP | Springer, R.Springer, Russ | 39 | Tanks | R | 79 | 62 | 0 | 6 | 0 | 2.04 | .241 | 0.92 | 5.8 | 2.5 | 7.5 | 84.0 | 54 | 22 | 19 | 10 | 23 | 70 | 0 | 2 | 2 | 0 | 0 | 3 | 1 | 3.81 |
| CL | Balfour, G.Balfour, Grant | 31 | Old Foes | R | 90 | 48 | 0 | 1 | 2 | 2.35 | .241 | 0.89 | 4.8 | 3.4 | 10.2 | 53.2 | 28 | 14 | 14 | 3 | 20 | 60 | 0 | 22 | 1 | 0 | 0 | 3 | 2 | 2.77 |
| CL | Soriano, R.Soriano, Rafael | 24 | Tanks | R | 97 | 46 | 0 | 4 | 7 | 5.40 | .341 | 1.47 | 9.0 | 4.3 | 10.9 | 48.1 | 48 | 30 | 29 | 6 | 23 | 58 | 0 | 20 | 4 | 0 | 0 | 4 | 0 | 3.90 |