| SP | Leonard, D.Leonard, Dutch | 22 | Classics | L | 84.0 | 16 | 16 | 11 | 1 | 3.05 | .274 | 1.12 | 6.4 | 3.6 | 5.6 | 112.0 | 80 | 42 | 38 | 12 | 45 | 70 | 1 | 0 | 0 | 1 | 11 | 2 | 2 | 4.40 |
| SP | Alexander, P.Alexander, Pete | 28 | Brahs | R | 61.0 | 15 | 15 | 7 | 5 | 2.98 | .286 | 1.17 | 8.0 | 2.6 | 4.8 | 111.2 | 99 | 38 | 37 | 8 | 32 | 59 | 7 | 0 | 0 | 1 | 10 | 3 | 0 | 3.82 |
| SP | Fernandez, J.Fernandez, Jose # | 21 | Dark Blues | R | 57.0 | 15 | 15 | 8 | 6 | 3.16 | .275 | 1.12 | 7.2 | 2.9 | 7.5 | 105.1 | 84 | 38 | 37 | 7 | 34 | 87 | 1 | 0 | 0 | 0 | 11 | 2 | 4 | 3.24 |
| SP | Verlander, J.Verlander, Justin | 36 | Suns | R | 57.0 | 16 | 16 | 7 | 4 | 3.58 | .300 | 1.27 | 8.5 | 3.1 | 7.5 | 115.2 | 108 | 50 | 46 | 7 | 39 | 96 | 4 | 0 | 0 | 1 | 10 | 2 | 1 | 3.19 |
| SP | Arrieta, J.Arrieta, Jake # | 29 | Dark Blues | R | 55.0 | 16 | 16 | 8 | 1 | 3.92 | .307 | 1.33 | 9.7 | 2.3 | 7.8 | 96.1 | 103 | 42 | 42 | 6 | 25 | 83 | 0 | 0 | 0 | 0 | 10 | 0 | 1 | 2.86 |
| SP | Koufax, S.Koufax, Sandy # | 30 | Lions | L | 54.0 | 16 | 16 | 7 | 5 | 4.01 | .289 | 1.20 | 7.9 | 3.0 | 7.9 | 130.1 | 114 | 61 | 58 | 15 | 43 | 114 | 5 | 0 | 0 | 1 | 10 | 2 | 1 | 3.78 |