| SP | Johnson, R.Johnson, Randy | 39 | Bolts | L | 225.0 | 35 | 35 | 23 | 7 | 2.43 | .238 | 0.92 | 5.7 | 2.6 | 10.9 | 270.2 | 172 | 88 | 73 | 25 | 77 | 327 | 16 | 0 | 0 | 4 | 28 | 4 | 5 | 2.68 |
| SP | Martinez, P.Martinez, Pedro | 31 | Whips | R | 144.0 | 36 | 36 | 16 | 11 | 2.81 | .266 | 1.06 | 7.2 | 2.4 | 9.2 | 249.2 | 199 | 93 | 78 | 21 | 66 | 255 | 3 | 0 | 0 | 2 | 26 | 7 | 5 | 2.93 |
| SP | Hernandez, O.Hernandez, Orlando | 37 | Bolts | R | 135.0 | 34 | 34 | 20 | 9 | 3.40 | .279 | 1.14 | 7.5 | 2.8 | 5.9 | 227.1 | 188 | 96 | 86 | 23 | 71 | 150 | 1 | 0 | 0 | 0 | 23 | 5 | 12 | 4.00 |
| SP | Washburn, J.Washburn, Jarrod | 28 | Whips | L | 133.0 | 33 | 33 | 21 | 8 | 3.84 | .308 | 1.31 | 8.8 | 3.1 | 6.7 | 218.0 | 212 | 103 | 93 | 22 | 74 | 163 | 2 | 0 | 0 | 1 | 21 | 5 | 5 | 3.90 |
| SP | Halladay, R.Halladay, Roy # | 25 | Oilers | R | 121.0 | 33 | 33 | 16 | 11 | 3.25 | .290 | 1.21 | 8.4 | 2.5 | 6.2 | 235.1 | 219 | 95 | 85 | 28 | 65 | 161 | 4 | 0 | 0 | 1 | 21 | 4 | 3 | 4.06 |
| SP | Schilling, C.Schilling, Curt | 36 | Gold Diggers | R | 116.0 | 36 | 36 | 17 | 14 | 3.82 | .313 | 1.31 | 9.2 | 2.6 | 10.3 | 254.1 | 261 | 125 | 108 | 22 | 72 | 290 | 2 | 0 | 0 | 0 | 21 | 15 | 5 | 2.87 |