| SP | Martinez, P.Martinez, Pedro | 29 | Elephants | R | 95.0 | 16 | 16 | 11 | 3 | 3.04 | .248 | 0.96 | 6.2 | 2.4 | 9.1 | 127.1 | 88 | 44 | 43 | 13 | 34 | 128 | 7 | 0 | 0 | 2 | 11 | 4 | 4 | 3.21 |
| SP | Santana, J.Santana, Johan | 25 | Warriors | L | 57.0 | 16 | 16 | 8 | 6 | 3.45 | .281 | 1.16 | 8.2 | 2.3 | 9.4 | 112.1 | 102 | 44 | 43 | 13 | 28 | 117 | 1 | 0 | 0 | 0 | 12 | 2 | 4 | 3.22 |
| SP | Hernandez, F.Hernandez, Felix # | 19 | Crabs | R | 44.0 | 16 | 16 | 6 | 7 | 3.51 | .292 | 1.22 | 8.1 | 2.9 | 7.6 | 118.0 | 106 | 46 | 46 | 14 | 38 | 99 | 1 | 0 | 0 | 0 | 9 | 2 | 0 | 3.88 |
| SP | Zambrano, C.Zambrano, Carlos # | 24 | Sharks | R | 41.0 | 16 | 16 | 7 | 7 | 4.15 | .302 | 1.28 | 8.7 | 2.8 | 7.5 | 106.1 | 103 | 51 | 49 | 9 | 33 | 88 | 2 | 0 | 0 | 2 | 9 | 2 | 4 | 3.43 |
| SP | Johnson, R.Johnson, Randy | 38 | Chieftains | L | 40.0 | 16 | 16 | 7 | 5 | 4.70 | .313 | 1.32 | 8.3 | 3.6 | 10.5 | 103.1 | 95 | 54 | 54 | 11 | 41 | 120 | 2 | 0 | 0 | 0 | 8 | 5 | 1 | 3.40 |
| SP | Sabathia, C.Sabathia, CC # | 28 | Cowboys | L | 39.0 | 16 | 16 | 7 | 4 | 4.72 | .318 | 1.37 | 10.0 | 2.4 | 8.8 | 108.2 | 120 | 60 | 57 | 16 | 29 | 105 | 1 | 0 | 0 | 0 | 6 | 3 | 4 | 3.87 |