| SP | Verlander, J.Verlander, Justin | 36 | Astros | R | 99 | 17 | 17 | 12 | 3 | 2.39 | .269 | 1.07 | 6.5 | 3.2 | 8.9 | 124.1 | 89 | 34 | 33 | 5 | 44 | 123 | 2 | 0 | 0 | 1 | 12 | 4 | 2 | 2.70 |
| SP | Driscoll, D.Driscoll, Denny | 27 | Buccos | L | 75 | 19 | 18 | 11 | 5 | 3.66 | .291 | 1.23 | 8.7 | 2.4 | 5.0 | 147.2 | 142 | 60 | 60 | 10 | 39 | 81 | 9 | 0 | 0 | 2 | 12 | 1 | 0 | 3.60 |
| SP | Johnson, R.Johnson, Randy # | 34 | Pilots | L | 76 | 19 | 19 | 11 | 6 | 2.83 | .267 | 1.08 | 6.8 | 3.0 | 10.0 | 143.1 | 108 | 45 | 45 | 9 | 47 | 159 | 4 | 0 | 0 | 2 | 15 | 2 | 3 | 2.62 |
| SP | Scherzer, M.Scherzer, Max | 38 | Metropolitans | R | 86 | 18 | 18 | 10 | 2 | 3.30 | .289 | 1.20 | 8.3 | 2.5 | 8.9 | 120.0 | 111 | 47 | 44 | 10 | 33 | 119 | 1 | 0 | 0 | 1 | 12 | 2 | 2 | 2.98 |
| CL | Delabar, S.Delabar, Steve | 28 | Pilots | R | 69 | 35 | 0 | 0 | 1 | 2.34 | .262 | 1.04 | 6.4 | 3.2 | 8.7 | 34.2 | 24 | 9 | 9 | 3 | 12 | 33 | 0 | 24 | 3 | 0 | 0 | 1 | 3 | 3.35 |
| CL | Hoffman, T.Hoffman, Trevor | 31 | Padres | R | 90 | 37 | 0 | 4 | 4 | 4.82 | .291 | 1.21 | 6.3 | 4.6 | 9.2 | 37.1 | 26 | 21 | 20 | 4 | 19 | 38 | 0 | 21 | 2 | 0 | 0 | 1 | 3 | 3.97 |