Scoreboard
| Final | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | x | R | H | E |
| Cubs (94-71) | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 4 | 1 |
| Astros (88-77) | 0 | 0 | 0 | 0 | 1 | 0 | 4 | 1 | 0 | 0 | 6 | 11 | 0 |
| W: Osuna (6-2) L: Hamels (13-12) GWRBI: Bregman | |||||||||||||
| HR: Cubs - Heyward (7) Bradley (16) Astros - Bregman (27) Hernandez (32) | |||||||||||||
| Box Score | |||||||||||||
| Final | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | x | R | H | E |
| Giants (81-82) | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 7 | 0 |
| Guardians (95-71) | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 8 | 0 |
| W: Anderson (16-10) L: Cain (13-15) SV: Clippard (12) GWRBI: Gonzalez | |||||||||||||
| HR: Guardians - Gonzalez (24) | |||||||||||||
| Box Score | |||||||||||||
| Final | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | x | R | H | E |
| Brewers (70-92) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 |
| Orioles (59-103) | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 |
| W: Tillman (13-13) L: Burnes (3-15) SV: Johnson (28) GWRBI: Roberts | |||||||||||||
| HR: None | |||||||||||||
| Box Score | |||||||||||||
| Final | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | x | R | H | E |
| White Sox (85-80) | 1 | 0 | 2 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 5 | 10 | 2 |
| Reds (82-80) | 4 | 0 | 2 | 0 | 0 | 6 | 2 | 0 | 0 | 0 | 14 | 10 | 0 |
| W: Greene (15-10) L: Cueto (12-11) GWRBI: Rolen | |||||||||||||
| HR: White Sox - Morneau (17) Delmonico (23) Reds - Bruce 2 (21) Dickerson (19) | |||||||||||||
| Box Score | |||||||||||||
| Final | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | x | R | H | E |
| Padres (102-68) | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 9 | 0 |
| Red Sox (57-105) | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5 | 0 |
| W: Snell (17-7) L: Wacha (7-19) SV: Castillo (8) GWRBI: Quentin | |||||||||||||
| HR: Padres - Spangenberg (9) Quentin (28) Red Sox - Drew (13) Pedroia (13) | |||||||||||||
| Box Score | |||||||||||||
| Final | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | x | R | H | E |
| Braves (101-71) | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 7 | 12 | 0 |
| Phillies (46-116) | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 1 | 0 | 6 | 9 | 0 |
| W: Strider (13-8) L: Oswalt (8-17) SV: Jansen (52) GWRBI: Olson | |||||||||||||
| HR: Braves - Acuna (41) McCann (20) | |||||||||||||
| Box Score | |||||||||||||
| Final | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | x | R | H | E |
| Royals (50-112) | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 4 | 1 |
| Blue Jays (82-80) | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 5 | 11 | 0 |
| W: Dotel (1-0) L: Hochevar (3-3) GWRBI: Travis | |||||||||||||
| HR: Royals - O'Hearn (10) Blue Jays - Springer (16) Travis (22) Tulowitzki (26) | |||||||||||||
| Box Score | |||||||||||||
| Final | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | x | R | H | E |
| Twins (61-101) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 |
| Angels (100-69) | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 7 | 0 |
| W: Lincecum (19-10) L: Pineda (8-13) GWRBI: Soto | |||||||||||||
| HR: Angels - Soto (15) | |||||||||||||
| Box Score | |||||||||||||
