| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 99 | 3 | 3 | 2 | 1 | 4.91 | .286 | 1.20 | 8.0 | 3.0 | 5.5 | 18.1 | 16 | 10 | 10 | 3 | 6 | 11 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 4.94 |
| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 92 | 3 | 3 | 3 | 0 | 1.78 | .269 | 1.11 | 8.3 | 1.8 | 11.5 | 25.1 | 23 | 5 | 5 | 1 | 5 | 32 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 1.56 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 71 | 2 | 2 | 1 | 1 | 2.93 | .292 | 1.24 | 8.4 | 3.0 | 4.2 | 15.1 | 14 | 5 | 5 | 1 | 5 | 7 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 3.93 |
| SP | Rogers, S.Rogers, Steve >> | 24 | 1973 | R | 41 | 2 | 2 | 2 | 0 | 6.59 | .339 | 1.54 | 10.4 | 4.2 | 4.8 | 13.2 | 15 | 10 | 10 | 1 | 6 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.31 |
| SP | Strasburg, S.Strasburg, Stephen >> | 24 | 2013 | R | 38 | 1 | 1 | 0 | 0 | 4.50 | .357 | 1.67 | 12.0 | 3.0 | 4.5 | 6.0 | 8 | 3 | 3 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.00 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 5 | 0 | 0 | 0 | 0.00 | .267 | 1.09 | 7.7 | 2.6 | 16.7 | 7.1 | 6 | 0 | 0 | 0 | 2 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0.14 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 88 | 7 | 0 | 0 | 0 | 5.63 | .294 | 1.25 | 7.9 | 3.4 | 3.4 | 8.0 | 7 | 5 | 5 | 1 | 3 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 65 | 3 | 0 | 1 | 0 | 0.00 | .308 | 1.33 | 6.0 | 6.0 | 12.0 | 3.0 | 2 | 0 | 0 | 0 | 2 | 4 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.33 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 64 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 40 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Valdez, S.Valdez, Sergio >> | 28 | 1992 | R | 17 | 1 | 0 | 0 | 0 | 0.00 | .250 | 1.00 | 0.0 | 9.0 | 9.0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.00 |