| SP | Arrieta, J.Arrieta, Jake # >> | 35 | 2015 | R | 87 | 15 | 15 | 4 | 5 | 4.82 | .333 | 1.48 | 9.3 | 4.1 | 6.6 | 99.0 | 102 | 54 | 53 | 8 | 45 | 73 | 1 | 0 | 0 | 0 | 7 | 1 | 4 | 3.97 |
| SP | Hendricks, K.Hendricks, Kyle >> | 32 | 2016 | R | 95 | 14 | 14 | 11 | 3 | 2.95 | .259 | 1.04 | 7.0 | 2.4 | 5.9 | 106.2 | 83 | 35 | 35 | 8 | 28 | 70 | 3 | 0 | 0 | 2 | 9 | 1 | 1 | 3.48 |
| SP | Sampson, A.Sampson, Adrian >> | 30 | 2021 | R | 82 | 14 | 14 | 3 | 6 | 5.01 | .294 | 1.23 | 8.4 | 2.7 | 3.8 | 59.1 | 55 | 33 | 33 | 11 | 18 | 25 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 5.54 |
| SP | Quintana, J.Quintana, Jose >> | 33 | 2017 | L | 39 | 14 | 14 | 7 | 4 | 4.84 | .338 | 1.52 | 10.7 | 3.0 | 9.8 | 83.2 | 99 | 45 | 45 | 14 | 28 | 90 | 0 | 0 | 0 | 0 | 6 | 1 | 1 | 4.07 |
| RP | Edwards, C.Edwards, Carl >> | 30 | 2016 | R | 100 | 36 | 0 | 5 | 4 | 2.22 | .245 | 0.93 | 4.2 | 4.2 | 9.3 | 69.0 | 32 | 18 | 17 | 5 | 32 | 71 | 0 | 7 | 2 | 0 | 0 | 3 | 3 | 3.41 |
| RP | Grimm, J.Grimm, Justin >> | 32 | 2015 | R | 97 | 34 | 0 | 2 | 0 | 3.86 | .326 | 1.45 | 7.0 | 6.1 | 8.3 | 49.0 | 38 | 21 | 21 | 3 | 33 | 45 | 0 | 4 | 0 | 0 | 0 | 0 | 4 | 3.98 |
| RP | Chapman, A.Chapman, Aroldis >> | 34 | 2016 | L | 96 | 26 | 0 | 3 | 1 | 3.73 | .266 | 1.09 | 5.2 | 4.6 | 8.1 | 31.1 | 18 | 13 | 13 | 4 | 16 | 28 | 0 | 7 | 1 | 0 | 0 | 0 | 5 | 4.42 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 34 | 2021 | R | 70 | 17 | 0 | 1 | 0 | 4.97 | .377 | 1.82 | 8.3 | 9.0 | 9.0 | 12.2 | 11 | 7 | 7 | 1 | 12 | 12 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 5.08 |
| RP | Tepera, R.Tepera, Ryan >> | 34 | 2021 | R | 65 | 8 | 0 | 0 | 2 | 6.48 | .306 | 1.08 | 4.5 | 5.6 | 2.3 | 8.1 | 4 | 6 | 6 | 2 | 5 | 2 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 8.38 |
| RP | Rondon, H.Rondon, Hector >> | 33 | 2015 | R | 86 | 7 | 0 | 0 | 0 | 1.13 | .294 | 1.25 | 6.8 | 4.5 | 13.5 | 8.0 | 6 | 1 | 1 | 0 | 4 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.50 |
| RP | Hughes, B.Hughes, Brandon >> | 26 | 2022 | L | 40 | 10 | 0 | 0 | 0 | 1.10 | .269 | 1.10 | 7.3 | 2.8 | 8.4 | 16.1 | 13 | 3 | 2 | 0 | 5 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.06 |