| CL | Miller, M.Miller, Mason † | Eruptions | R | 155.5 | 62 | 0 | 6 | 4 | 1.87 | .271 | 1.07 | 4.8 | 4.9 | 10.6 | 62.2 | 33 | 13 | 13 | 0 | 34 | 73 | 0 | 43 | 1 | 0 | 0 | 3 | 1 | 2.44 |
| SP | Skubal, T.Skubal, Tarik † | Bees | L | 136.0 | 28 | 28 | 16 | 5 | 2.88 | .278 | 1.10 | 7.5 | 2.4 | 11.6 | 190.2 | 159 | 62 | 61 | 22 | 51 | 244 | 1 | 0 | 0 | 1 | 19 | 10 | 4 | 2.90 |
| CL | Thielbar, C.Thielbar, Caleb † | Scooters | L | 123.5 | 56 | 0 | 4 | 3 | 2.28 | .245 | 0.94 | 5.9 | 2.6 | 8.8 | 55.1 | 36 | 14 | 14 | 4 | 16 | 54 | 0 | 37 | 3 | 0 | 0 | 2 | 0 | 2.96 |
| SP | Crochet, G.Crochet, Garrett † # | Elephants | L | 106.0 | 28 | 28 | 13 | 7 | 3.28 | .295 | 1.24 | 8.4 | 2.8 | 11.6 | 186.2 | 173 | 70 | 68 | 12 | 58 | 240 | 0 | 0 | 0 | 0 | 17 | 3 | 1 | 2.24 |
| SP | deGrom, J.deGrom, Jacob † | Elephants | R | 91.0 | 28 | 28 | 11 | 8 | 3.06 | .296 | 1.20 | 7.4 | 3.4 | 10.2 | 170.2 | 140 | 63 | 58 | 14 | 65 | 193 | 0 | 0 | 0 | 0 | 14 | 10 | 0 | 3.12 |
| SP | Imanaga, S.Imanaga, Shota † | Spirit | L | 86.0 | 26 | 26 | 13 | 5 | 3.91 | .294 | 1.23 | 8.4 | 2.6 | 8.4 | 159.0 | 149 | 71 | 69 | 20 | 46 | 149 | 0 | 0 | 0 | 0 | 15 | 4 | 0 | 3.70 |